Mesenchymal Stem Cells Loaded in Injectable Alginate Hydrogels Promote Liver Growth and Attenuate Liver Fibrosis in Cirrhotic Rats

Mesenchymal Stem Cells Loaded in Injectable Alginate Hydrogels Promote Liver Growth and Attenuate Liver Fibrosis in Cirrhotic Rats

Cirrhosis, a marker of severe liver diseases, limits future liver remnant (FLR) growth, preventing many cancer patients from undergoing surgery. While portal vein blockade (PVB) techniques are used to stimulate liver regeneration, 20–30% of patients still fail to achieve the required growth. Althoug...

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Bibliographic Details
Main Authors: Dominic Karl M. Bolinas, Allan John R. Barcena, Archana Mishra, Marvin R. Bernardino, Vincent Lin, Francisco M. Heralde, Gouthami Chintalapani, Natalie W. Fowlkes, Steven Y. Huang, Marites P. Melancon
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Gels
Subjects:
alginate
hydrogel
mesenchymal stem cells
liver cirrhosis
Online Access:https://www.mdpi.com/2310-2861/11/4/250
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