An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique
This review article recapitulates the analytical methods for the quantitative determinations of diltiazem and three H2 receptor antagonists (cimetidine, ranitidine, and famotidine) by one of the spectroscopic technique (UV spectrophotometery) and separation technique such as high-performance liquid...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/184948 |
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| author | Nighat Shafi Farhan Ahmed Siddiqui Huma Naseem Nawab Sher Arif Zubair Azhar Hussain Ali Akbar Sial Mirza Tasawer Baig |
| author_facet | Nighat Shafi Farhan Ahmed Siddiqui Huma Naseem Nawab Sher Arif Zubair Azhar Hussain Ali Akbar Sial Mirza Tasawer Baig |
| author_sort | Nighat Shafi |
| collection | DOAJ |
| description | This review article recapitulates the analytical methods for the quantitative determinations of diltiazem and three H2 receptor antagonists (cimetidine, ranitidine, and famotidine) by one of the spectroscopic technique (UV spectrophotometery) and separation technique such as high-performance liquid chromatography (HPLC). The clinical and pharmaceutical analysis of these drugs requires effective analytical procedures for quality control, pharmaceutical dosage formulations, and biological fluids. An extensive survey of the literature published in various analytical and pharmaceutical chemistry-related journals has been compiled in its review. A synopsis of reported spectrophotometric and high-performance liquid chromatographic methods for individual drug is integrated. This appraisal illustrates that majority of the HPLC methods reviewed are based on the quantitative analysis of drugs in biological fluids, and they are appropriate for therapeutic drug monitoring purpose. |
| format | Article |
| id | doaj-art-ecbe9ed230ab4174a4342be636b65cea |
| institution | DOAJ |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-ecbe9ed230ab4174a4342be636b65cea2025-08-20T03:21:26ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/184948184948An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC TechniqueNighat Shafi0Farhan Ahmed Siddiqui1Huma Naseem2Nawab Sher3Arif Zubair4Azhar Hussain5Ali Akbar Sial6Mirza Tasawer Baig7Faculty of Pharmacy, Federal Urdu University Arts Science and Technology, Karachi 75300, PakistanFaculty of Pharmacy, Federal Urdu University Arts Science and Technology, Karachi 75300, PakistanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi, Karachi 75270, PakistanDepartment of Chemistry, University of Karachi, Karachi 75270, PakistanDepartment of Environmental Sciences, Faculty of Science, Federal Urdu University Arts Science and Technology, Karachi 75300, PakistanDepartment of Pharmaceutics, Faculty of Pharmacy, University of Karachi, Karachi 75270, PakistanFaculty of Pharmacy, Federal Urdu University Arts Science and Technology, Karachi 75300, PakistanFaculty of Pharmacy, Federal Urdu University Arts Science and Technology, Karachi 75300, PakistanThis review article recapitulates the analytical methods for the quantitative determinations of diltiazem and three H2 receptor antagonists (cimetidine, ranitidine, and famotidine) by one of the spectroscopic technique (UV spectrophotometery) and separation technique such as high-performance liquid chromatography (HPLC). The clinical and pharmaceutical analysis of these drugs requires effective analytical procedures for quality control, pharmaceutical dosage formulations, and biological fluids. An extensive survey of the literature published in various analytical and pharmaceutical chemistry-related journals has been compiled in its review. A synopsis of reported spectrophotometric and high-performance liquid chromatographic methods for individual drug is integrated. This appraisal illustrates that majority of the HPLC methods reviewed are based on the quantitative analysis of drugs in biological fluids, and they are appropriate for therapeutic drug monitoring purpose.http://dx.doi.org/10.1155/2013/184948 |
| spellingShingle | Nighat Shafi Farhan Ahmed Siddiqui Huma Naseem Nawab Sher Arif Zubair Azhar Hussain Ali Akbar Sial Mirza Tasawer Baig An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique Journal of Chemistry |
| title | An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique |
| title_full | An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique |
| title_fullStr | An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique |
| title_full_unstemmed | An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique |
| title_short | An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique |
| title_sort | overview of analytical determination of diltiazem cimetidine ranitidine and famotidine by uv spectrophotometry and hplc technique |
| url | http://dx.doi.org/10.1155/2013/184948 |
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