The development of microbiological methods for drug analysis

The article presents the review of the national regulatory documents on drug testing for microbiological characteristics, such as «Sterility», «Microbiological Purity» etc. It discusses the history of the establishment of characteristics and the elaboration of the related general pharmacopoeia monog...

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Main Authors: O. V. Gunar, N. G. Sakhno, E. S. Novik, G. M. Bulgakova, L. V. Kolosova, I. A. Buylova, M. V. Roshchina
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2018-02-01
Series:Регуляторные исследования и экспертиза лекарственных средств
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Online Access:https://www.vedomostincesmp.ru/jour/article/view/6
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author O. V. Gunar
N. G. Sakhno
E. S. Novik
G. M. Bulgakova
L. V. Kolosova
I. A. Buylova
M. V. Roshchina
author_facet O. V. Gunar
N. G. Sakhno
E. S. Novik
G. M. Bulgakova
L. V. Kolosova
I. A. Buylova
M. V. Roshchina
author_sort O. V. Gunar
collection DOAJ
description The article presents the review of the national regulatory documents on drug testing for microbiological characteristics, such as «Sterility», «Microbiological Purity» etc. It discusses the history of the establishment of characteristics and the elaboration of the related general pharmacopoeia monographs, as well as prospects for the development of methods in connection with the publication of the Russian State Pharmacopoeia XIII edition. There is a clear trend towards harmonization with the leading world pharmacopoeias, but the Russian State Pharmacopoeia maintains the individual characteristics of drug quality analysis in terms of microbiological characteristics, including the introduction of new technologies, process automation and taking into account the special features of individual drug groups.
format Article
id doaj-art-ecb6a36d0ad4433384d191b52faa25fe
institution Kabale University
issn 3034-3062
3034-3453
language Russian
publishDate 2018-02-01
publisher Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)
record_format Article
series Регуляторные исследования и экспертиза лекарственных средств
spelling doaj-art-ecb6a36d0ad4433384d191b52faa25fe2025-08-20T03:39:44ZrusFederal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)Регуляторные исследования и экспертиза лекарственных средств3034-30623034-34532018-02-010115184The development of microbiological methods for drug analysisO. V. Gunar0N. G. Sakhno1E. S. Novik2G. M. Bulgakova3L. V. Kolosova4I. A. Buylova5M. V. Roshchina6Scientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsThe article presents the review of the national regulatory documents on drug testing for microbiological characteristics, such as «Sterility», «Microbiological Purity» etc. It discusses the history of the establishment of characteristics and the elaboration of the related general pharmacopoeia monographs, as well as prospects for the development of methods in connection with the publication of the Russian State Pharmacopoeia XIII edition. There is a clear trend towards harmonization with the leading world pharmacopoeias, but the Russian State Pharmacopoeia maintains the individual characteristics of drug quality analysis in terms of microbiological characteristics, including the introduction of new technologies, process automation and taking into account the special features of individual drug groups.https://www.vedomostincesmp.ru/jour/article/view/6микробиологические показателистерильностьмикробиологическая чистотасодержание витаминовконцентрация микробных клетокэффективность консервантовmicrobiological characteristicssterilitymicrobiological purityvitamin contentconcentration of microbial cellspreservative effectiveness
spellingShingle O. V. Gunar
N. G. Sakhno
E. S. Novik
G. M. Bulgakova
L. V. Kolosova
I. A. Buylova
M. V. Roshchina
The development of microbiological methods for drug analysis
Регуляторные исследования и экспертиза лекарственных средств
микробиологические показатели
стерильность
микробиологическая чистота
содержание витаминов
концентрация микробных клеток
эффективность консервантов
microbiological characteristics
sterility
microbiological purity
vitamin content
concentration of microbial cells
preservative effectiveness
title The development of microbiological methods for drug analysis
title_full The development of microbiological methods for drug analysis
title_fullStr The development of microbiological methods for drug analysis
title_full_unstemmed The development of microbiological methods for drug analysis
title_short The development of microbiological methods for drug analysis
title_sort development of microbiological methods for drug analysis
topic микробиологические показатели
стерильность
микробиологическая чистота
содержание витаминов
концентрация микробных клеток
эффективность консервантов
microbiological characteristics
sterility
microbiological purity
vitamin content
concentration of microbial cells
preservative effectiveness
url https://www.vedomostincesmp.ru/jour/article/view/6
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