Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders

Saved in:
Bibliographic Details
Main Authors: Ruonan Wang, Zhongyi Jian, Yanlian Yang, Chen Wang, Lanlan Yu, Mingzhan Wang, Chenxuan Wang
Format: Article
Language:English
Published: American Chemical Society 2025-05-01
Series:ACS Central Science
Online Access:https://doi.org/10.1021/acscentsci.5c00421
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849424072460468224
author Ruonan Wang
Zhongyi Jian
Yanlian Yang
Chen Wang
Lanlan Yu
Mingzhan Wang
Chenxuan Wang
author_facet Ruonan Wang
Zhongyi Jian
Yanlian Yang
Chen Wang
Lanlan Yu
Mingzhan Wang
Chenxuan Wang
author_sort Ruonan Wang
collection DOAJ
format Article
id doaj-art-ecb660c4e92b4b7c8a904700f1bd3292
institution Kabale University
issn 2374-7951
language English
publishDate 2025-05-01
publisher American Chemical Society
record_format Article
series ACS Central Science
spelling doaj-art-ecb660c4e92b4b7c8a904700f1bd32922025-08-20T03:30:20ZengAmerican Chemical SocietyACS Central Science2374-79512025-05-0111692793710.1021/acscentsci.5c00421Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation DisordersRuonan Wang0Zhongyi Jian1Yanlian Yang2Chen Wang3Lanlan Yu4Mingzhan Wang5Chenxuan Wang6State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, P. R. ChinaState Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, P. R. ChinaCAS Key Laboratory of Biological Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, P. R. ChinaCAS Key Laboratory of Biological Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, P. R. ChinaState Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, P. R. ChinaCenter of Super-Diamond and Advanced Films (COSDAF), Department of Materials Science and Engineering, City University of Hong Kong, Kowloon, Hong Kong, P. R. ChinaState Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, P. R. Chinahttps://doi.org/10.1021/acscentsci.5c00421
spellingShingle Ruonan Wang
Zhongyi Jian
Yanlian Yang
Chen Wang
Lanlan Yu
Mingzhan Wang
Chenxuan Wang
Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders
ACS Central Science
title Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders
title_full Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders
title_fullStr Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders
title_full_unstemmed Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders
title_short Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders
title_sort submolecular resolution of β sheet plasticity decoding mutations and ptms in protein aggregation disorders
url https://doi.org/10.1021/acscentsci.5c00421
work_keys_str_mv AT ruonanwang submolecularresolutionofbsheetplasticitydecodingmutationsandptmsinproteinaggregationdisorders
AT zhongyijian submolecularresolutionofbsheetplasticitydecodingmutationsandptmsinproteinaggregationdisorders
AT yanlianyang submolecularresolutionofbsheetplasticitydecodingmutationsandptmsinproteinaggregationdisorders
AT chenwang submolecularresolutionofbsheetplasticitydecodingmutationsandptmsinproteinaggregationdisorders
AT lanlanyu submolecularresolutionofbsheetplasticitydecodingmutationsandptmsinproteinaggregationdisorders
AT mingzhanwang submolecularresolutionofbsheetplasticitydecodingmutationsandptmsinproteinaggregationdisorders
AT chenxuanwang submolecularresolutionofbsheetplasticitydecodingmutationsandptmsinproteinaggregationdisorders