DNAzyme hydrogels specifically inhibit the NLRP3 pathway to prevent radiation-induced skin injury in mice

Abstract Radiation-induced skin injury (RISI) is a frequent complication of radiotherapy, yet current preventive strategies exhibit suboptimal efficacy. Our previous publications have consistently demonstrated the effectiveness of biomaterials and hydrogels in preventing RISI. Based on comprehensive...

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Bibliographic Details
Main Authors: Daijun Zhou, Zhihui Li, Linbo Bao, Xiang Zhao, Jie Hao, Chuan Xu, Feifan Sun, Dan He, Chaoyang Jiang, Tian Zeng, Dong Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-025-03147-x
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