Clinical features of endobronchial tuberculosis
Background/Aim. Endobronchial tuberculosis (EBTB) is a specific type of pulmonary tuberculosis which often affect the tracheobronchial tree, and can be microbiologically and/or pathohistologically confirmed. The aim of the study was to determine the clinical features and diagnostic aspects...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2014-01-01
|
| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501402156S.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850227147494391808 |
|---|---|
| author | Samardžić Natalija Jovanović Dragana Marković-Denić Ljiljana Roksandić-Milenković Marina Popević Spasoje Škodrić-Trifunović Vesna |
| author_facet | Samardžić Natalija Jovanović Dragana Marković-Denić Ljiljana Roksandić-Milenković Marina Popević Spasoje Škodrić-Trifunović Vesna |
| author_sort | Samardžić Natalija |
| collection | DOAJ |
| description | Background/Aim. Endobronchial tuberculosis (EBTB) is a specific type of
pulmonary tuberculosis which often affect the tracheobronchial tree, and can
be microbiologically and/or pathohistologically confirmed. The aim of the
study was to determine the clinical features and diagnostic aspects of EBTB.
Methods. This retrospective study was conducted at the Clinic for Lung
Diseases, Clinical Center of Serbia, Belgrade, from January 1997 to December
2007. All patients with EBTB confirmed by bronchoscopy with biopsy during a
study period were analysed. Data included the patient’s medical history, a
physical exam, chest X-ray, mycobacterial analysis of sputum samples,
endoscopic types and patohistological confirmation. Results. In the study,
57.6% of the patients were males. The most frequent symptoms were cough
(71.2%), malaise (54.2%), fever (49.2%), weight loss (40.7%), and hemoptysis
(13.6%). Most of the patients were diagnosed within 30 days of symptoms
onset. Sputum examination showed acid-fast bacilli in 31.4% of the patients,
while sputum culture for tuberculosis bacilli were positive in 55.9% of the
patients. The most common radiographic localization was in the upper lung
lobes (63.5%). Cavities were present in 60.4% of the patients. The most
common endoscopic subtype determined by bronchoscopy were nonspecific
bronchitis (39.9%) and edematous-hyperemic subtype (36.4%). Conclusion. EBTB
was more frequent among men, and among people in their fifties in our
country. Detailed bronchoscopic examination, correlated with clinical and
laboratory findings, will improve diagnostic rate and provide timely therapy.
[Projekat Ministarstva nauke Republike Srbije, br. 175046] |
| format | Article |
| id | doaj-art-eca6b8fa7fb7448aac670b4d0945267c |
| institution | OA Journals |
| issn | 0042-8450 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-eca6b8fa7fb7448aac670b4d0945267c2025-08-20T02:04:54ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502014-01-0171215616010.2298/VSP1402156S0042-84501402156SClinical features of endobronchial tuberculosisSamardžić Natalija0Jovanović Dragana1Marković-Denić Ljiljana2Roksandić-Milenković Marina3Popević Spasoje4Škodrić-Trifunović Vesna5Clinic for Lung Disease, Clinical Center of Serbia, BelgradeClinical Center of Serbia, Clinic for Lung Disease, Belgrade + Faculty of Medicine, BelgradeFaculty of Medicine, Belgrade + Faculty of Medicine, Institute of Epidemiology, BelgradeClinic for Lung Disease, Clinical Center of Serbia, BelgradeClinic for Lung Disease, Clinical Center of Serbia, BelgradeClinical Center of Serbia, Clinic for Lung Disease, Belgrade + Faculty of Medicine, BelgradeBackground/Aim. Endobronchial tuberculosis (EBTB) is a specific type of pulmonary tuberculosis which often affect the tracheobronchial tree, and can be microbiologically and/or pathohistologically confirmed. The aim of the study was to determine the clinical features and diagnostic aspects of EBTB. Methods. This retrospective study was conducted at the Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, from January 1997 to December 2007. All patients with EBTB confirmed by bronchoscopy with biopsy during a study period were analysed. Data included the patient’s medical history, a physical exam, chest X-ray, mycobacterial analysis of sputum samples, endoscopic types and patohistological confirmation. Results. In the study, 57.6% of the patients were males. The most frequent symptoms were cough (71.2%), malaise (54.2%), fever (49.2%), weight loss (40.7%), and hemoptysis (13.6%). Most of the patients were diagnosed within 30 days of symptoms onset. Sputum examination showed acid-fast bacilli in 31.4% of the patients, while sputum culture for tuberculosis bacilli were positive in 55.9% of the patients. The most common radiographic localization was in the upper lung lobes (63.5%). Cavities were present in 60.4% of the patients. The most common endoscopic subtype determined by bronchoscopy were nonspecific bronchitis (39.9%) and edematous-hyperemic subtype (36.4%). Conclusion. EBTB was more frequent among men, and among people in their fifties in our country. Detailed bronchoscopic examination, correlated with clinical and laboratory findings, will improve diagnostic rate and provide timely therapy. [Projekat Ministarstva nauke Republike Srbije, br. 175046]http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501402156S.pdftuberculosis, pulmonarydiagnosissigns and symptomsradiographybronhoscopyhistological techniques |
| spellingShingle | Samardžić Natalija Jovanović Dragana Marković-Denić Ljiljana Roksandić-Milenković Marina Popević Spasoje Škodrić-Trifunović Vesna Clinical features of endobronchial tuberculosis Vojnosanitetski Pregled tuberculosis, pulmonary diagnosis signs and symptoms radiography bronhoscopy histological techniques |
| title | Clinical features of endobronchial tuberculosis |
| title_full | Clinical features of endobronchial tuberculosis |
| title_fullStr | Clinical features of endobronchial tuberculosis |
| title_full_unstemmed | Clinical features of endobronchial tuberculosis |
| title_short | Clinical features of endobronchial tuberculosis |
| title_sort | clinical features of endobronchial tuberculosis |
| topic | tuberculosis, pulmonary diagnosis signs and symptoms radiography bronhoscopy histological techniques |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501402156S.pdf |
| work_keys_str_mv | AT samardzicnatalija clinicalfeaturesofendobronchialtuberculosis AT jovanovicdragana clinicalfeaturesofendobronchialtuberculosis AT markovicdenicljiljana clinicalfeaturesofendobronchialtuberculosis AT roksandicmilenkovicmarina clinicalfeaturesofendobronchialtuberculosis AT popevicspasoje clinicalfeaturesofendobronchialtuberculosis AT skodrictrifunovicvesna clinicalfeaturesofendobronchialtuberculosis |