Clinical features of endobronchial tuberculosis
Background/Aim. Endobronchial tuberculosis (EBTB) is a specific type of pulmonary tuberculosis which often affect the tracheobronchial tree, and can be microbiologically and/or pathohistologically confirmed. The aim of the study was to determine the clinical features and diagnostic aspects...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2014-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501402156S.pdf |
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| Summary: | Background/Aim. Endobronchial tuberculosis (EBTB) is a specific type of
pulmonary tuberculosis which often affect the tracheobronchial tree, and can
be microbiologically and/or pathohistologically confirmed. The aim of the
study was to determine the clinical features and diagnostic aspects of EBTB.
Methods. This retrospective study was conducted at the Clinic for Lung
Diseases, Clinical Center of Serbia, Belgrade, from January 1997 to December
2007. All patients with EBTB confirmed by bronchoscopy with biopsy during a
study period were analysed. Data included the patient’s medical history, a
physical exam, chest X-ray, mycobacterial analysis of sputum samples,
endoscopic types and patohistological confirmation. Results. In the study,
57.6% of the patients were males. The most frequent symptoms were cough
(71.2%), malaise (54.2%), fever (49.2%), weight loss (40.7%), and hemoptysis
(13.6%). Most of the patients were diagnosed within 30 days of symptoms
onset. Sputum examination showed acid-fast bacilli in 31.4% of the patients,
while sputum culture for tuberculosis bacilli were positive in 55.9% of the
patients. The most common radiographic localization was in the upper lung
lobes (63.5%). Cavities were present in 60.4% of the patients. The most
common endoscopic subtype determined by bronchoscopy were nonspecific
bronchitis (39.9%) and edematous-hyperemic subtype (36.4%). Conclusion. EBTB
was more frequent among men, and among people in their fifties in our
country. Detailed bronchoscopic examination, correlated with clinical and
laboratory findings, will improve diagnostic rate and provide timely therapy.
[Projekat Ministarstva nauke Republike Srbije, br. 175046] |
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| ISSN: | 0042-8450 |