Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis
Introduction: Epidural analgesia has been studied for its potential advantages after surgery in a number of random ized clinical trials, with most finding improvements in pain and secondary endpoints like the incidence of postoper ative complications. Aim: To assess the relationship between use...
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| Format: | Article |
| Language: | English |
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Medycyna Praktyczna
2024-03-01
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| Series: | Videosurgery and Other Miniinvasive Techniques |
| Subjects: | |
| Online Access: | https://www.mp.pl/videosurgery/issue/article/17839/ |
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| _version_ | 1849333582471888896 |
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| author | Qiong Hu Xuqi Yu Ting Zhou |
| author_facet | Qiong Hu Xuqi Yu Ting Zhou |
| author_sort | Qiong Hu |
| collection | DOAJ |
| description | Introduction: Epidural analgesia has been studied for its potential advantages after surgery in a number of random
ized clinical trials, with most finding improvements in pain and secondary endpoints like the incidence of postoper
ative complications.
Aim: To assess the relationship between use of epidural analgesia and adverse cardiac outcomes expressed by myo
cardial infarction (MI).
Material and methods: Fifty-three studies were recruited to quantify the influence of different surgical-related anal
gesic methods on clinical parameters (mortality and adverse events). The results of these trials were analysed using
a random effects model, which was then used to calculate the mean difference (MD) with 95 per cent confidence
intervals (CIs).
Results: Epidural analgesia resulted in preferred cardiac outcomes compared with traditional analgesia. These find
ings were supported by significantly lower MI events for the epidural analgesia group as follows: p = 0.005, p = 0,007,
and p = 0.03 for the total number of included studies, studies with high risk of bias, and studies with low risk of bias,
respectively. Studies with intermediate risk showed a non-significant difference between both groups (p = 0.7).
Conclusions: Epidural analgesia has a significant protective cardiac effect through the reduction of postoperative MI
events among surgery subjects. |
| format | Article |
| id | doaj-art-ec9f52491fd444d9bb7bec04e74e9cb5 |
| institution | Kabale University |
| issn | 1895-4588 2299-0054 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Medycyna Praktyczna |
| record_format | Article |
| series | Videosurgery and Other Miniinvasive Techniques |
| spelling | doaj-art-ec9f52491fd444d9bb7bec04e74e9cb52025-08-20T03:45:48ZengMedycyna PraktycznaVideosurgery and Other Miniinvasive Techniques1895-45882299-00542024-03-01191112410.5114/wiitm.2024.13597752527Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysisQiong Hu0Xuqi Yu1Ting Zhou2Department of Anaesthesiology, Women and Children’s Hospital of Ningbo University, Zhejiang, ChinaDepartment of Anaesthesiology, Women and Children’s Hospital of Ningbo University, Zhejiang, ChinaDepartment of Emergency, Ningbo Medical Treatment Centre Lihuili Hospital, Zhejiang, China Introduction: Epidural analgesia has been studied for its potential advantages after surgery in a number of random ized clinical trials, with most finding improvements in pain and secondary endpoints like the incidence of postoper ative complications. Aim: To assess the relationship between use of epidural analgesia and adverse cardiac outcomes expressed by myo cardial infarction (MI). Material and methods: Fifty-three studies were recruited to quantify the influence of different surgical-related anal gesic methods on clinical parameters (mortality and adverse events). The results of these trials were analysed using a random effects model, which was then used to calculate the mean difference (MD) with 95 per cent confidence intervals (CIs). Results: Epidural analgesia resulted in preferred cardiac outcomes compared with traditional analgesia. These find ings were supported by significantly lower MI events for the epidural analgesia group as follows: p = 0.005, p = 0,007, and p = 0.03 for the total number of included studies, studies with high risk of bias, and studies with low risk of bias, respectively. Studies with intermediate risk showed a non-significant difference between both groups (p = 0.7). Conclusions: Epidural analgesia has a significant protective cardiac effect through the reduction of postoperative MI events among surgery subjects.https://www.mp.pl/videosurgery/issue/article/17839/epidural analgesiageneralised analgesiamyocardial infarctionmortalityefficacy |
| spellingShingle | Qiong Hu Xuqi Yu Ting Zhou Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis Videosurgery and Other Miniinvasive Techniques epidural analgesia generalised analgesia myocardial infarction mortality efficacy |
| title | Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis |
| title_full | Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis |
| title_fullStr | Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis |
| title_full_unstemmed | Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis |
| title_short | Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis |
| title_sort | epidural analgesia during surgery and its relation to postoperative myocardial infarction meta analysis |
| topic | epidural analgesia generalised analgesia myocardial infarction mortality efficacy |
| url | https://www.mp.pl/videosurgery/issue/article/17839/ |
| work_keys_str_mv | AT qionghu epiduralanalgesiaduringsurgeryanditsrelationtopostoperativemyocardialinfarctionmetaanalysis AT xuqiyu epiduralanalgesiaduringsurgeryanditsrelationtopostoperativemyocardialinfarctionmetaanalysis AT tingzhou epiduralanalgesiaduringsurgeryanditsrelationtopostoperativemyocardialinfarctionmetaanalysis |