Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China

Since its first recognition, the 2009 pandemic influenza A (H1N1) virus rapidly spread worldwide. We observed the clinical characteristics of 167 hospitalized patients who were confirmed by testing pharyngeal or nasopharyngeal swabs with the use of a real-time reverse-transcriptase polymerase...

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Main Authors: Zhihua Wang, Xiaoqing Li, Dan Li, Yahong Li
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2012-04-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/1603
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author Zhihua Wang
Xiaoqing Li
Dan Li
Yahong Li
author_facet Zhihua Wang
Xiaoqing Li
Dan Li
Yahong Li
author_sort Zhihua Wang
collection DOAJ
description Since its first recognition, the 2009 pandemic influenza A (H1N1) virus rapidly spread worldwide. We observed the clinical characteristics of 167 hospitalized patients who were confirmed by testing pharyngeal or nasopharyngeal swabs with the use of a real-time reverse-transcriptase polymerase chain reaction (RT-PCR) assay. The mean age of the 167 hospitalized patients was 4.1 years, and 58.7% were male. The most common symptoms and signs were fever (91.6%), cough (82.6%), pharyngeal congestion (95.2%), and swollen tonsils (34.1%). The major complications were bronchitis (19.2%), bronchial pneumonia (10.8%), neutropenia (49.7%), and leukopenia (38.9%). The duration of hospitalization, fever and the course of disease in the patients who were treated with oseltamivir were shorter than in those who were treated with ribavirin. All of the patients fully recuperated from the 2009 epidemic influenza A (H1N1) infection with one exception.
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publisher Hacettepe University Institute of Child Health
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spelling doaj-art-ec9c38ac15c5467799fbaf729fdf16e22025-08-20T03:01:15ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212012-04-01542Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, ChinaZhihua Wang0Xiaoqing LiDan LiYahong LiThe Fourth Department of Infectious Diseases, Xi'an Children's Hospital Affiliated with the School of Medicine, Xi'an Jiaotong University, Xi'an, China. Since its first recognition, the 2009 pandemic influenza A (H1N1) virus rapidly spread worldwide. We observed the clinical characteristics of 167 hospitalized patients who were confirmed by testing pharyngeal or nasopharyngeal swabs with the use of a real-time reverse-transcriptase polymerase chain reaction (RT-PCR) assay. The mean age of the 167 hospitalized patients was 4.1 years, and 58.7% were male. The most common symptoms and signs were fever (91.6%), cough (82.6%), pharyngeal congestion (95.2%), and swollen tonsils (34.1%). The major complications were bronchitis (19.2%), bronchial pneumonia (10.8%), neutropenia (49.7%), and leukopenia (38.9%). The duration of hospitalization, fever and the course of disease in the patients who were treated with oseltamivir were shorter than in those who were treated with ribavirin. All of the patients fully recuperated from the 2009 epidemic influenza A (H1N1) infection with one exception. https://turkjpediatr.org/article/view/1603
spellingShingle Zhihua Wang
Xiaoqing Li
Dan Li
Yahong Li
Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China
The Turkish Journal of Pediatrics
title Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China
title_full Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China
title_fullStr Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China
title_full_unstemmed Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China
title_short Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China
title_sort clinical features of 167 children with the novel influenza a h1n1 virus infection in xi an china
url https://turkjpediatr.org/article/view/1603
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