Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES database
Background Human papillomavirus (HPV) is one of the most prevalent sexually transmitted infections (STIs). Individuals with depression face higher risks of other STIs; however, the relationship between depression and HPV remains unclear.Objective To investigate the association between depression and...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Journal of Psychosomatic Obstetrics and Gynecology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/0167482X.2025.2541955 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849405783525031936 |
|---|---|
| author | Xu Yu Jingya Nie Lifang Zhou Yubin Mao Yanping Jiang |
| author_facet | Xu Yu Jingya Nie Lifang Zhou Yubin Mao Yanping Jiang |
| author_sort | Xu Yu |
| collection | DOAJ |
| description | Background Human papillomavirus (HPV) is one of the most prevalent sexually transmitted infections (STIs). Individuals with depression face higher risks of other STIs; however, the relationship between depression and HPV remains unclear.Objective To investigate the association between depression and HPV among American women.Methods Data were sourced from the National Health and Nutrition Examination Survey (NHANES) conducted from 2005 to 2016. We employed weighted logistic regression models to explore the relationship between depression scores, depressive states, depression severity and HPV infection risk. The stability of intergroup relationships was assessed by subgroup analyses.Results Seven thousand and twenty-four American women were included, including 3138 HPV-positive individuals. Logistic regression analyses revealed a significant positive correlation between increased depression scores (OR = 1.02, 95% CI: 1.00–1.03, p = .009) and the presence of depression (OR = 1.33, 95% CI: 1.07–1.65, p = .010) with HPV infection risk. The HPV infection risk was elevated in the moderate depression group (OR = 1.32, 95% CI = 1.02–1.70, p = .036). Subgroup analyses indicated that marital status, body mass index and sexual activity frequency interacted with the relationship between depression and HPV (p-interaction < .05).Conclusions Our findings highlight an association between depression and increased HPV infection risk among American women, underscoring the importance of enhancing HPV protection awareness among women with depression. |
| format | Article |
| id | doaj-art-ec99d2ea46144dd7b8efd073964a577f |
| institution | Kabale University |
| issn | 0167-482X 1743-8942 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Psychosomatic Obstetrics and Gynecology |
| spelling | doaj-art-ec99d2ea46144dd7b8efd073964a577f2025-08-20T03:36:34ZengTaylor & Francis GroupJournal of Psychosomatic Obstetrics and Gynecology0167-482X1743-89422025-12-0146110.1080/0167482X.2025.2541955Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES databaseXu Yu0Jingya Nie1Lifang Zhou2Yubin Mao3Yanping Jiang4Department of Pathology, Huzhou Nanxun People’s Hospital, Huzhou, ChinaDepartment of Gynecology, Huzhou Nanxun People’s Hospital, Huzhou, ChinaDepartment of Pathology, Huzhou Nanxun People’s Hospital, Huzhou, ChinaDepartment of Pathology, Huzhou Nanxun People’s Hospital, Huzhou, ChinaDepartment of Pathology, Huzhou Nanxun People’s Hospital, Huzhou, ChinaBackground Human papillomavirus (HPV) is one of the most prevalent sexually transmitted infections (STIs). Individuals with depression face higher risks of other STIs; however, the relationship between depression and HPV remains unclear.Objective To investigate the association between depression and HPV among American women.Methods Data were sourced from the National Health and Nutrition Examination Survey (NHANES) conducted from 2005 to 2016. We employed weighted logistic regression models to explore the relationship between depression scores, depressive states, depression severity and HPV infection risk. The stability of intergroup relationships was assessed by subgroup analyses.Results Seven thousand and twenty-four American women were included, including 3138 HPV-positive individuals. Logistic regression analyses revealed a significant positive correlation between increased depression scores (OR = 1.02, 95% CI: 1.00–1.03, p = .009) and the presence of depression (OR = 1.33, 95% CI: 1.07–1.65, p = .010) with HPV infection risk. The HPV infection risk was elevated in the moderate depression group (OR = 1.32, 95% CI = 1.02–1.70, p = .036). Subgroup analyses indicated that marital status, body mass index and sexual activity frequency interacted with the relationship between depression and HPV (p-interaction < .05).Conclusions Our findings highlight an association between depression and increased HPV infection risk among American women, underscoring the importance of enhancing HPV protection awareness among women with depression.https://www.tandfonline.com/doi/10.1080/0167482X.2025.2541955DepressionHPVNHANESAmerican womenRisk factors |
| spellingShingle | Xu Yu Jingya Nie Lifang Zhou Yubin Mao Yanping Jiang Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES database Journal of Psychosomatic Obstetrics and Gynecology Depression HPV NHANES American women Risk factors |
| title | Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES database |
| title_full | Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES database |
| title_fullStr | Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES database |
| title_full_unstemmed | Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES database |
| title_short | Association between mental health and HPV in American women: an analysis based on the 2005–2016 NHANES database |
| title_sort | association between mental health and hpv in american women an analysis based on the 2005 2016 nhanes database |
| topic | Depression HPV NHANES American women Risk factors |
| url | https://www.tandfonline.com/doi/10.1080/0167482X.2025.2541955 |
| work_keys_str_mv | AT xuyu associationbetweenmentalhealthandhpvinamericanwomenananalysisbasedonthe20052016nhanesdatabase AT jingyanie associationbetweenmentalhealthandhpvinamericanwomenananalysisbasedonthe20052016nhanesdatabase AT lifangzhou associationbetweenmentalhealthandhpvinamericanwomenananalysisbasedonthe20052016nhanesdatabase AT yubinmao associationbetweenmentalhealthandhpvinamericanwomenananalysisbasedonthe20052016nhanesdatabase AT yanpingjiang associationbetweenmentalhealthandhpvinamericanwomenananalysisbasedonthe20052016nhanesdatabase |