The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study).
Background and objectives: The present study aimed to investigate the efficacy of local use of propolis (PRO) as adjunctive to scaling and root planing (SRP) in the treatment of alveolar bone loss in rats with ligature induced periodontitis (LIP). Material and methods: 60 male rats were divided in...
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College Of Dentistry Hawler Medical University
2022-07-01
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| Series: | Erbil Dental Journal |
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| Online Access: | https://edj.hmu.edu.krd/index.php/journal/article/view/165 |
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| author | Khadeeja Mohammed Ali Zewar Ahmad Saleh Jalal Ali Jalal |
| author_facet | Khadeeja Mohammed Ali Zewar Ahmad Saleh Jalal Ali Jalal |
| author_sort | Khadeeja Mohammed Ali |
| collection | DOAJ |
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Background and objectives: The present study aimed to investigate the efficacy of local use of propolis (PRO) as adjunctive to scaling and root planing (SRP) in the treatment of alveolar bone loss in rats with ligature induced periodontitis (LIP).
Material and methods: 60 male rats were divided into three groups of 20 rats: the control group (C) with no experimental periodontitis or treatment (gp1); ligature-induced periodontitis treated by SRP with a vehicle irrigation (dimethyl sulfoxide + physiological saline solution) group (gp2); and ligature-induced periodontitis treated by SRP with 10% PRO extract irrigation group (gp3). The irrigation materials were locally applied three times daily for 11 days After removal of the ligature, SRP was performed in gp2 and gp3. Five rats from each group were euthanized on days 0, 7, 14, and 21 after local treatment. Intracardiac blood samples and mandible were obtained for biochemical and histopatholical analysis.
Results: Rats that received local treatment by SRP with propolis irrigation in gp3 revealed features of acceleration of the periodontal tissue-repair process, alveolar bone formation, and significantly higher alkaline phosphatase serum levels (ALP) than gp2 were treated by SRP with vehicle irrigation.
Conclusion: Local use of propolis as an adjunct therapy to SRP can be effective in the treatment of alveolar bone loss in rat model of ligature-induced periodontitis.
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| format | Article |
| id | doaj-art-ec997ab776594061a6d49d31def96fd0 |
| institution | Kabale University |
| issn | 2523-6172 2616-4795 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | College Of Dentistry Hawler Medical University |
| record_format | Article |
| series | Erbil Dental Journal |
| spelling | doaj-art-ec997ab776594061a6d49d31def96fd02025-02-10T20:48:25ZengCollege Of Dentistry Hawler Medical UniversityErbil Dental Journal2523-61722616-47952022-07-0151The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study).Khadeeja Mohammed Ali0Zewar Ahmad Saleh1Jalal Ali Jalal2Department of Periodontology, College of Dentistry, Hawler Medical University, Erbil, Iraq.Department of Periodontology, College of Dentistry, Hawler Medical University, Erbil, Iraq. Department of Basic Sciences, College of Medicine, Hawler Medical University, Erbil, Iraq. Background and objectives: The present study aimed to investigate the efficacy of local use of propolis (PRO) as adjunctive to scaling and root planing (SRP) in the treatment of alveolar bone loss in rats with ligature induced periodontitis (LIP). Material and methods: 60 male rats were divided into three groups of 20 rats: the control group (C) with no experimental periodontitis or treatment (gp1); ligature-induced periodontitis treated by SRP with a vehicle irrigation (dimethyl sulfoxide + physiological saline solution) group (gp2); and ligature-induced periodontitis treated by SRP with 10% PRO extract irrigation group (gp3). The irrigation materials were locally applied three times daily for 11 days After removal of the ligature, SRP was performed in gp2 and gp3. Five rats from each group were euthanized on days 0, 7, 14, and 21 after local treatment. Intracardiac blood samples and mandible were obtained for biochemical and histopatholical analysis. Results: Rats that received local treatment by SRP with propolis irrigation in gp3 revealed features of acceleration of the periodontal tissue-repair process, alveolar bone formation, and significantly higher alkaline phosphatase serum levels (ALP) than gp2 were treated by SRP with vehicle irrigation. Conclusion: Local use of propolis as an adjunct therapy to SRP can be effective in the treatment of alveolar bone loss in rat model of ligature-induced periodontitis. https://edj.hmu.edu.krd/index.php/journal/article/view/165Alveolar bone resorptionAlkaline phosphatase enzymeLigature induced periodontitisPropolis |
| spellingShingle | Khadeeja Mohammed Ali Zewar Ahmad Saleh Jalal Ali Jalal The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study). Erbil Dental Journal Alveolar bone resorption Alkaline phosphatase enzyme Ligature induced periodontitis Propolis |
| title | The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study). |
| title_full | The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study). |
| title_fullStr | The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study). |
| title_full_unstemmed | The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study). |
| title_short | The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study). |
| title_sort | effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats a biochemical and histological study |
| topic | Alveolar bone resorption Alkaline phosphatase enzyme Ligature induced periodontitis Propolis |
| url | https://edj.hmu.edu.krd/index.php/journal/article/view/165 |
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