Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialis

The effects of heterotrophic transformation and autotrophic transformation on astaxanthin production in Haematococcus pluvialis were studied and compared. When sodium acetate was added in MCM for heterotrophic transformation, astaxanthin accumulation was increased from 0.723 6 mg·L<sup>-1</...

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Main Authors: ZHANG Rui-qin, GUAN Bin, KONG Qing, YOU Yong, WU Ji-qin, WEI Qun
Format: Article
Language:English
Published: Zhejiang University Press 2011-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2011.06.006
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author ZHANG Rui-qin
GUAN Bin
KONG Qing
YOU Yong
WU Ji-qin
WEI Qun
author_facet ZHANG Rui-qin
GUAN Bin
KONG Qing
YOU Yong
WU Ji-qin
WEI Qun
author_sort ZHANG Rui-qin
collection DOAJ
description The effects of heterotrophic transformation and autotrophic transformation on astaxanthin production in Haematococcus pluvialis were studied and compared. When sodium acetate was added in MCM for heterotrophic transformation, astaxanthin accumulation was increased from 0.723 6 mg·L<sup>-1</sup> to 1.216 8 mg·L<sup>-1</sup>. To enhance the astaxanthin accumulation, single factor experiment was founded up. Center composite design experiments and response surface methodology were employed to optimize the media of heterotrophic transformation. The results showed a distinctive influence of sodium acetate and potassium nitrate concentrations on astaxanthin accumulation. The optimal fermentation medium consisted of 1.460 5 g·L<sup>-1</sup> sodium acetate, 0.008 4 g·L<sup>-1</sup> potassium nitrate, and 0.02 g·L<sup>-1</sup> potassium dihydrogen phosphate. Astaxanthin content reached 10.908 mg·L<sup>-1</sup>, which was raised 10.16-fold against the control group and 14.07-fold against the group of autotrophic transformation.
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series 浙江大学学报. 农业与生命科学版
spelling doaj-art-ec96a27824ed4ae3bb724ae241d014e72025-08-20T03:33:21ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552011-11-013762463010.3785/j.issn.1008-9209.2011.06.00610089209Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialisZHANG Rui-qinGUAN BinKONG QingYOU YongWU Ji-qinWEI QunThe effects of heterotrophic transformation and autotrophic transformation on astaxanthin production in Haematococcus pluvialis were studied and compared. When sodium acetate was added in MCM for heterotrophic transformation, astaxanthin accumulation was increased from 0.723 6 mg·L<sup>-1</sup> to 1.216 8 mg·L<sup>-1</sup>. To enhance the astaxanthin accumulation, single factor experiment was founded up. Center composite design experiments and response surface methodology were employed to optimize the media of heterotrophic transformation. The results showed a distinctive influence of sodium acetate and potassium nitrate concentrations on astaxanthin accumulation. The optimal fermentation medium consisted of 1.460 5 g·L<sup>-1</sup> sodium acetate, 0.008 4 g·L<sup>-1</sup> potassium nitrate, and 0.02 g·L<sup>-1</sup> potassium dihydrogen phosphate. Astaxanthin content reached 10.908 mg·L<sup>-1</sup>, which was raised 10.16-fold against the control group and 14.07-fold against the group of autotrophic transformation.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2011.06.006<italic>Haematococcus pluvialis</italic>astaxanthinsodium acetateheterotrophic transformationresponse surface methodology (RSM)
spellingShingle ZHANG Rui-qin
GUAN Bin
KONG Qing
YOU Yong
WU Ji-qin
WEI Qun
Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialis
浙江大学学报. 农业与生命科学版
<italic>Haematococcus pluvialis</italic>
astaxanthin
sodium acetate
heterotrophic transformation
response surface methodology (RSM)
title Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialis
title_full Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialis
title_fullStr Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialis
title_full_unstemmed Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialis
title_short Study on astaxanthin accumulation by heterotrophic transformation in Haematococcus pluvialis
title_sort study on astaxanthin accumulation by heterotrophic transformation in haematococcus pluvialis
topic <italic>Haematococcus pluvialis</italic>
astaxanthin
sodium acetate
heterotrophic transformation
response surface methodology (RSM)
url https://www.academax.com/doi/10.3785/j.issn.1008-9209.2011.06.006
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