Preparation of robust synthetic control samples and their use in a metatranscriptomic clinical test

Abstract Metatranscriptomics (MT) has the potential to revolutionize the field of molecular diagnostics. Due to the complexity of MT diagnostic models, positive and negative control materials for specific disease indications can be difficult to obtain. Controls must often be sourced directly from pa...

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Bibliographic Details
Main Authors: Ryan Toma, Lan Hu, Guru Banavar, Momchilo Vuyisich
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-95020-y
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