A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium Topographies
The major challenge for dental implants is achieving optimal esthetic appearance and a concept to fulfill this criterion is evaluated. The key to an esthetically pleasing appearance lies in the properly manage the soft tissue profile around dental implants. A novel implant restoration technique on t...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2012/687291 |
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| author | Fu-Yuan Teng Chia-Ling Ko Hsien-Nan Kuo Jin-Jia Hu Jia-Horng Lin Ching-Wen Lou Chun-Cheng Hung Yin-Lai Wang Cheng-Yi Cheng Wen-Cheng Chen |
| author_facet | Fu-Yuan Teng Chia-Ling Ko Hsien-Nan Kuo Jin-Jia Hu Jia-Horng Lin Ching-Wen Lou Chun-Cheng Hung Yin-Lai Wang Cheng-Yi Cheng Wen-Cheng Chen |
| author_sort | Fu-Yuan Teng |
| collection | DOAJ |
| description | The major challenge for dental implants is achieving optimal esthetic appearance and a concept to fulfill this criterion is evaluated. The key to an esthetically pleasing appearance lies in the properly manage the soft tissue profile around dental implants. A novel implant restoration technique on the surface was proposed as a way to augment both soft- and hard-tissue profiles at potential implant sites. Different levels of roughness can be attained by sandblasting and acid etching, and a tetracalcium phosphate was used to supply the ions. In particular, the early stage attaching and repopulating abilities of bone cell osteoblasts (MC3T3-E1), fibroblasts (NIH 3T3), and epithelial cells (XB-2) were evaluated. The results showed that XB-2 cell adhesive qualities of a smooth surface were better than those of the roughened surfaces, the proliferative properties were reversed. The effects of roughness on the characteristics of 3T3 cells were opposite to the result for XB-2 cells. E1 proliferative ability did not differ with any statistical significance. These results suggest that a rougher surface which provided calcium and phosphate ions have the ability to enhance the proliferation of osteoblast and the inhibition of fibroblast growth that enhance implant success ratios. |
| format | Article |
| id | doaj-art-ec9368cc9e5d492da73a5d755291890d |
| institution | OA Journals |
| issn | 1565-3633 1687-479X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-ec9368cc9e5d492da73a5d755291890d2025-08-20T02:21:49ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2012-01-01201210.1155/2012/687291687291A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium TopographiesFu-Yuan Teng0Chia-Ling Ko1Hsien-Nan Kuo2Jin-Jia Hu3Jia-Horng Lin4Ching-Wen Lou5Chun-Cheng Hung6Yin-Lai Wang7Cheng-Yi Cheng8Wen-Cheng Chen9Department of Dentistry, Kaohsiung Armed Forces General Hospital, Kaohsiung 802, TaiwanSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807, TaiwanMedical Device Development Division, Metal Industries Research & Development Centre, Kaohsiung 82151, TaiwanDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, TaiwanLaboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials, Feng Chia University, School of Chinese Medicine, China Medical University, Taichung 40724, TaiwanInstitute of Biomedical Engineering and Material Science, Central Taiwan University of Science and Technology, Taichung 40601, TaiwanSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807, TaiwanDepartment of Dentistry, Kaohsiung Armed Forces General Hospital, Kaohsiung 802, TaiwanSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807, TaiwanDepartment of Fiber and Composite Materials, College of Engineering, Feng Chia University, 100 Wenhwa Road., Seatwen, Taichung 40724, TaiwanThe major challenge for dental implants is achieving optimal esthetic appearance and a concept to fulfill this criterion is evaluated. The key to an esthetically pleasing appearance lies in the properly manage the soft tissue profile around dental implants. A novel implant restoration technique on the surface was proposed as a way to augment both soft- and hard-tissue profiles at potential implant sites. Different levels of roughness can be attained by sandblasting and acid etching, and a tetracalcium phosphate was used to supply the ions. In particular, the early stage attaching and repopulating abilities of bone cell osteoblasts (MC3T3-E1), fibroblasts (NIH 3T3), and epithelial cells (XB-2) were evaluated. The results showed that XB-2 cell adhesive qualities of a smooth surface were better than those of the roughened surfaces, the proliferative properties were reversed. The effects of roughness on the characteristics of 3T3 cells were opposite to the result for XB-2 cells. E1 proliferative ability did not differ with any statistical significance. These results suggest that a rougher surface which provided calcium and phosphate ions have the ability to enhance the proliferation of osteoblast and the inhibition of fibroblast growth that enhance implant success ratios.http://dx.doi.org/10.1155/2012/687291 |
| spellingShingle | Fu-Yuan Teng Chia-Ling Ko Hsien-Nan Kuo Jin-Jia Hu Jia-Horng Lin Ching-Wen Lou Chun-Cheng Hung Yin-Lai Wang Cheng-Yi Cheng Wen-Cheng Chen A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium Topographies Bioinorganic Chemistry and Applications |
| title | A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium Topographies |
| title_full | A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium Topographies |
| title_fullStr | A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium Topographies |
| title_full_unstemmed | A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium Topographies |
| title_short | A Comparison of Epithelial Cells, Fibroblasts, and Osteoblasts in Dental Implant Titanium Topographies |
| title_sort | comparison of epithelial cells fibroblasts and osteoblasts in dental implant titanium topographies |
| url | http://dx.doi.org/10.1155/2012/687291 |
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