Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast China
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease with high case fatality rate. In 2016, a series of community-based comprehensive measures were put into effect in Daishan. This study was conducted to explore the change in the epidemiology of...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | Ticks and Tick-Borne Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1877959X25000457 |
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| author | Qilong Tan Shuqin Fu Jiwei Shu Ying Liu Yihan Lou Mingxing Hu Sen Zhang Jimin Sun Jiangping Ren |
| author_facet | Qilong Tan Shuqin Fu Jiwei Shu Ying Liu Yihan Lou Mingxing Hu Sen Zhang Jimin Sun Jiangping Ren |
| author_sort | Qilong Tan |
| collection | DOAJ |
| description | Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease with high case fatality rate. In 2016, a series of community-based comprehensive measures were put into effect in Daishan. This study was conducted to explore the change in the epidemiology of SFTS following the implementation of those measures.. Methods: Descriptive and statistical analyses were conducted to characterize the epidemiology of SFTS. Results: In total, 156 cases were reported in Daishan during 2011–2023, with the average annual incidence rate of 66.58 per million. The incidence increased with age, and the case fatality rate was significantly higher among the cases over 65 years (P < 0.050). After the implementation of the community-based comprehensive measures in 2016, the incidence was remarkably declined from 2015 to 2019 (Annual Percent Change [APC] = -39.98, P < 0.001) and remained relatively stable without significant alteration between 2019 and 2023 (APC = 15.77, P = 0.156), which was in contrast to the trends in Zhejiang and Mainland China. The hospital type that was most frequently visited for the initial medical-seeking shifted from type I (59.26 %) in 2011–2016 to type II (56.52 %) in 2017–2023. The time intervals between first-visiting and confirmation, onset and confirmation were shortened in the period of 2017–2023 (P < 0.001). Consequently, the case fatality was insignificantly reduced (8.70 % vs. 20 %, P = 0.084). Conclusions: The community-based comprehensive measures are highly efficacious in the containment of SFTS. |
| format | Article |
| id | doaj-art-ec8c67f648e24ac5b3de5f79fdf55a46 |
| institution | OA Journals |
| issn | 1877-9603 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ticks and Tick-Borne Diseases |
| spelling | doaj-art-ec8c67f648e24ac5b3de5f79fdf55a462025-08-20T02:02:24ZengElsevierTicks and Tick-Borne Diseases1877-96032025-05-0116310248110.1016/j.ttbdis.2025.102481Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast ChinaQilong Tan0Shuqin Fu1Jiwei Shu2Ying Liu3Yihan Lou4Mingxing Hu5Sen Zhang6Jimin Sun7Jiangping Ren8Daishan County Center for Disease Control and Prevention, Zhoushan, PR ChinaDaishan County Hospital of Traditional Chinese Medicine, Zhoushan, PR ChinaDaishan County Center for Disease Control and Prevention, Zhoushan, PR ChinaZhejiang Key Lab of Vaccine, Infectious Disease Prevention and Control, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, PR ChinaZhejiang Key Lab of Vaccine, Infectious Disease Prevention and Control, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, PR ChinaDinghai District Center for Disease Control and Prevention, Zhoushan, PR ChinaDinghai District Center for Disease Control and Prevention, Zhoushan, PR ChinaZhejiang Key Lab of Vaccine, Infectious Disease Prevention and Control, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, PR China; Corresponding authors.Zhejiang Key Lab of Vaccine, Infectious Disease Prevention and Control, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, PR China; Corresponding authors.Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease with high case fatality rate. In 2016, a series of community-based comprehensive measures were put into effect in Daishan. This study was conducted to explore the change in the epidemiology of SFTS following the implementation of those measures.. Methods: Descriptive and statistical analyses were conducted to characterize the epidemiology of SFTS. Results: In total, 156 cases were reported in Daishan during 2011–2023, with the average annual incidence rate of 66.58 per million. The incidence increased with age, and the case fatality rate was significantly higher among the cases over 65 years (P < 0.050). After the implementation of the community-based comprehensive measures in 2016, the incidence was remarkably declined from 2015 to 2019 (Annual Percent Change [APC] = -39.98, P < 0.001) and remained relatively stable without significant alteration between 2019 and 2023 (APC = 15.77, P = 0.156), which was in contrast to the trends in Zhejiang and Mainland China. The hospital type that was most frequently visited for the initial medical-seeking shifted from type I (59.26 %) in 2011–2016 to type II (56.52 %) in 2017–2023. The time intervals between first-visiting and confirmation, onset and confirmation were shortened in the period of 2017–2023 (P < 0.001). Consequently, the case fatality was insignificantly reduced (8.70 % vs. 20 %, P = 0.084). Conclusions: The community-based comprehensive measures are highly efficacious in the containment of SFTS.http://www.sciencedirect.com/science/article/pii/S1877959X25000457Severe fever with thrombocytopenia syndromeChinaEpidemiologyIncidenceCase fatality rate |
| spellingShingle | Qilong Tan Shuqin Fu Jiwei Shu Ying Liu Yihan Lou Mingxing Hu Sen Zhang Jimin Sun Jiangping Ren Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast China Ticks and Tick-Borne Diseases Severe fever with thrombocytopenia syndrome China Epidemiology Incidence Case fatality rate |
| title | Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast China |
| title_full | Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast China |
| title_fullStr | Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast China |
| title_full_unstemmed | Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast China |
| title_short | Effective control of severe fever with thrombocytopenia syndrome in Daishan County, a former epicenter in Zhejiang Province, Southeast China |
| title_sort | effective control of severe fever with thrombocytopenia syndrome in daishan county a former epicenter in zhejiang province southeast china |
| topic | Severe fever with thrombocytopenia syndrome China Epidemiology Incidence Case fatality rate |
| url | http://www.sciencedirect.com/science/article/pii/S1877959X25000457 |
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