Skeletal Muscle mRNA Splicing Variants Association With Four Different Fitness and Energetic Measures in the GESTALT Study

Skeletal Muscle mRNA Splicing Variants Association With Four Different Fitness and Energetic Measures in the GESTALT Study

ABSTRACT Background Physical activity is essential for maintaining muscle mitochondrial function and aerobic capacity. The molecular mechanisms underlying such protective effects are incompletely understood, in part because it is difficult to separate the effects of disease status and physical activ...

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Main Authors: Stefano Donega, Nirad Banskota, Esha Gupta, Marta Gonzalez‐Freire, Ann Zenobia Moore, Ceereena Ubaida‐Mohien, Rachel Munk, Linda Zukley, Yulan Piao, Chris Bergeron, Jan Bergeron, Arsun Bektas, Marta Zampino, Carole Stagg, Fred Indig, Lisa M. Hartnell, Mary Kaileh, Kenneth Fishbein, Richard G. Spencer, Myriam Gorospe, Supriyo De, Josephine M. Egan, Ranjan Sen, Luigi Ferrucci
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
aging
alternative splicing
energy
exercise
kPCr
mitochondria respirometry
Online Access:https://doi.org/10.1002/jcsm.13603
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