Development a glycosylated extracellular vesicle-derived miRNA Signature for early detection of esophageal squamous cell carcinoma

Development a glycosylated extracellular vesicle-derived miRNA Signature for early detection of esophageal squamous cell carcinoma

Abstract Background Esophageal squamous cell carcinoma (ESCC) is often diagnosed at an advanced stage due to the lack of non-invasive early detection tools, which significantly impacts patient prognosis. Given that glycosylation alterations especially high sialylation and fucosylation, frequently oc...

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Bibliographic Details
Main Authors: Jianlin Chen, Yue Zheng, Zhen Wang, Qi Gao, Kun Hao, Xiongfeng Chen, Nantian Ke, Xiang Lv, Jiamiao Weng, Yuhong Zhong, Zhixin Huang, Miao Fu, Lilan Zhao, Fan Lin, Hui Mi, Haijun Tang, Chundong Yu, Yi Huang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medicine
Subjects:
Glycosylated EVs capture
miRNA
Liquid biopsy
Early diagnosis
Esophageal squamous cell carcinoma
Online Access:https://doi.org/10.1186/s12916-025-03871-z
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