POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEW
Faloak bark (Sterculia quadrifida R. Br) is part of the faloak plant, which has been used for a long time in traditional medicine to treat a variety of medical conditions. Faloak bark is claimed to possess medicinal properties that can treat liver, kidney, and bladder diseases, cure gastroenteritis...
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Universitas Muhammadiyah Magelang
2025-04-01
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| Series: | Jurnal Farmasi Sains dan Praktis |
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| Online Access: | https://journal.unimma.ac.id/index.php/pharmacy/article/view/10862 |
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| author | Shofiatul Fuadah Rochmy Istikharah Priska Ernestina Tenda Arba Pramundita Ramadani |
| author_facet | Shofiatul Fuadah Rochmy Istikharah Priska Ernestina Tenda Arba Pramundita Ramadani |
| author_sort | Shofiatul Fuadah |
| collection | DOAJ |
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Faloak bark (Sterculia quadrifida R. Br) is part of the faloak plant, which has been used for a long time in traditional medicine to treat a variety of medical conditions. Faloak bark is claimed to possess medicinal properties that can treat liver, kidney, and bladder diseases, cure gastroenteritis, hepatitis, anemia, malaria, back pain, and function as an energy booster. Recent studies in pharmacology have found that faloak bark has several interesting biological properties, thus strengthening its potential as a new source of active ingredients for pharmaceutical development. This study literature aims to provide a concise overview of the evaluations of the secondary metabolite chemicals found in faloak bark, thus highlighting their potential pharmacological properties. To find articles for the review of the pharmacological activities of faloak bark, a search was conducted on research journal databases using Publish or Perish 8, and 43 papers relevant to the evaluation were found. Literature review showed that faloak bark contains many different chemicals, such as alkaloids, gallic acid derivatives, flavonoids, polyphenols, saponins, steroids, tannins, terpenoids, triterpenoids, quinone, glycoside, as well as isolates of 2,3-dihydro-6-hydroxy-2-methylenenaphtho[1,2-b] furan-4,5-dione, and 2-iminoethyl 2-(1-hydroxypentan-2-yl) phenyl) acetate. Faloak bark has such pharmacological properties as antiaging, antibacterial, antibiofilm, anti-dengue, antifungal, anti-hepatitis C, anti-hyperglycemia, anticancer, antimalarial, antioxidant, antipyretic, and immunomodulatory effects. Therefore, faloak bark has considerable potential for the advancement of herbal remedies.
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| format | Article |
| id | doaj-art-ec7b74b962e345fe978298e09c36fe59 |
| institution | Kabale University |
| issn | 2549-9068 2579-4558 |
| language | Indonesian |
| publishDate | 2025-04-01 |
| publisher | Universitas Muhammadiyah Magelang |
| record_format | Article |
| series | Jurnal Farmasi Sains dan Praktis |
| spelling | doaj-art-ec7b74b962e345fe978298e09c36fe592025-08-20T03:51:59ZindUniversitas Muhammadiyah MagelangJurnal Farmasi Sains dan Praktis2549-90682579-45582025-04-0111110.31603/pharmacy.v11i1.10862POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEWShofiatul Fuadah0Rochmy Istikharah1Priska Ernestina Tenda2Arba Pramundita Ramadani3Master’s Program in Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia, 55584Department of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia, 55584Department of Pharmacy, Poltekkes Kemenkes Kupang, East Nusa Tenggara, 85361Department of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia, 55584 Faloak bark (Sterculia quadrifida R. Br) is part of the faloak plant, which has been used for a long time in traditional medicine to treat a variety of medical conditions. Faloak bark is claimed to possess medicinal properties that can treat liver, kidney, and bladder diseases, cure gastroenteritis, hepatitis, anemia, malaria, back pain, and function as an energy booster. Recent studies in pharmacology have found that faloak bark has several interesting biological properties, thus strengthening its potential as a new source of active ingredients for pharmaceutical development. This study literature aims to provide a concise overview of the evaluations of the secondary metabolite chemicals found in faloak bark, thus highlighting their potential pharmacological properties. To find articles for the review of the pharmacological activities of faloak bark, a search was conducted on research journal databases using Publish or Perish 8, and 43 papers relevant to the evaluation were found. Literature review showed that faloak bark contains many different chemicals, such as alkaloids, gallic acid derivatives, flavonoids, polyphenols, saponins, steroids, tannins, terpenoids, triterpenoids, quinone, glycoside, as well as isolates of 2,3-dihydro-6-hydroxy-2-methylenenaphtho[1,2-b] furan-4,5-dione, and 2-iminoethyl 2-(1-hydroxypentan-2-yl) phenyl) acetate. Faloak bark has such pharmacological properties as antiaging, antibacterial, antibiofilm, anti-dengue, antifungal, anti-hepatitis C, anti-hyperglycemia, anticancer, antimalarial, antioxidant, antipyretic, and immunomodulatory effects. Therefore, faloak bark has considerable potential for the advancement of herbal remedies. https://journal.unimma.ac.id/index.php/pharmacy/article/view/10862Pharmacology activitySecondary metabolismSterculia quadrifida R. Br |
| spellingShingle | Shofiatul Fuadah Rochmy Istikharah Priska Ernestina Tenda Arba Pramundita Ramadani POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEW Jurnal Farmasi Sains dan Praktis Pharmacology activity Secondary metabolism Sterculia quadrifida R. Br |
| title | POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEW |
| title_full | POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEW |
| title_fullStr | POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEW |
| title_full_unstemmed | POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEW |
| title_short | POTENTIAL PHARMACOLOGICAL ACTIVITIES OF FALOAK BARK (STERCULIA QUADRIFIDA R. BR) AS AN HERBAL PLANT FROM EAST NUSA TENGGARA: A SCOPING REVIEW |
| title_sort | potential pharmacological activities of faloak bark sterculia quadrifida r br as an herbal plant from east nusa tenggara a scoping review |
| topic | Pharmacology activity Secondary metabolism Sterculia quadrifida R. Br |
| url | https://journal.unimma.ac.id/index.php/pharmacy/article/view/10862 |
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