<i>APOE</i> Polymorphism, Obstructive Sleep Apnea, and Cognitive Function

<i>APOE</i> Polymorphism, Obstructive Sleep Apnea, and Cognitive Function

Objective Obstructive sleep apnea (OSA) is associated with the apolipoprotein E ε4 polymorphic allele (APOE ε4) and with worse cognitive function. However, the influence of APOE ε4 on cognitive function in patients with moderate-to-severe OSA is controversial. The present study evaluated...

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Main Authors: Elisangela Macedo Gara, Thiago Tanaka Goya, Rosyvaldo Ferreira-Silva, Larissa Matheus, Renato Marques Jordão, Marlon Lemos Araújo, Alanna Joselle Silva, Renan Segalla Guerra, Geraldo Lorenzi-Filho, Linda Massako Ueno-Pardi
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2025-03-01
Series:Sleep Science
Subjects:
sleep
cognition
apolipoprotein
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788286
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Summary:Objective Obstructive sleep apnea (OSA) is associated with the apolipoprotein E ε4 polymorphic allele (APOE ε4) and with worse cognitive function. However, the influence of APOE ε4 on cognitive function in patients with moderate-to-severe OSA is controversial. The present study evaluated the influence of APOE ε4 polymorphism and cognitive function in sedentary OSA patients with no other major comorbidities.
ISSN:1984-0659
1984-0063

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