Machine learning based on pangenome-wide association studies reveals the impact of host source on the zoonotic potential of closely related bacterial pathogens

Abstract Variations in host species significantly impact bacterial growth traits and antibiotic resistance, making it essential to consider host origin when evaluating the zoonotic potential of pathogens. This study focuses on multiple Brucella species, which share highly similar genetic material, t...

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Bibliographic Details
Main Authors: Cheng Han, Shiying Lu, Pan Hu, Jiang Chang, Deying Zou, Feng Li, Yansong Li, Qiang Lu, Honglin Ren
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08650-3
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