Irisin Prevents the Effects of Simulated Microgravity on Bone and Muscle Differentiation Markers

Irisin Prevents the Effects of Simulated Microgravity on Bone and Muscle Differentiation Markers

ABSTRACT Microgravity exposure affects both tissues and cells, and, in this regard, one of the most affected targets is the skeletal muscle system due to the significant loss of bone and muscle mass leading to osteoporosis and sarcopenia, respectively. Several efforts are underway to counteract the...

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Bibliographic Details
Main Authors: Lorenzo Sanesi, Roberta Zerlotin, Alessio Campiolo, Angela Oranger, Manuela Dicarlo, Clelia Suriano, Ameneh Ghadiri, Graziana Colaianni, Maria Grano, Sara Tavella, Silvia Colucci
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:FASEB BioAdvances
Subjects:
bone
irisin
microgravity
muscle
myoblasts
osteoblasts
Online Access:https://doi.org/10.1096/fba.2025-00085
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