Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer Patients

ABSTRACT Introduction Objective was to describe the association between baseline characteristics and the number of Symptom Screening in Pediatrics Tool (SSPedi) assessments completed over an 8‐week period. Methods This was a sub‐analysis of a cluster randomized controlled trial among 10 sites that w...

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Main Authors: L. Lee Dupuis, Emily Vettese, Catherine Aftandilian, Vibhuti Agarwal, Christina Baggott, Scott M. Bradfield, Nicole Crellin‐Parsons, David R. Freyer, Kara M. Kelly, Allison A. King, Wade Kyono, Ramamoorthy Nagasubramanian, Etan Orgel, Michael E. Roth, Farha Sherani, Lolie Yu, Allison C. Grimes, Melissa P. Beauchemin, Lisa M. Klesges, George A. Tomlinson, Lillian Sung
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Cancer Medicine
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Online Access:https://doi.org/10.1002/cam4.71053
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author L. Lee Dupuis
Emily Vettese
Catherine Aftandilian
Vibhuti Agarwal
Christina Baggott
Scott M. Bradfield
Nicole Crellin‐Parsons
David R. Freyer
Kara M. Kelly
Allison A. King
Wade Kyono
Ramamoorthy Nagasubramanian
Etan Orgel
Michael E. Roth
Farha Sherani
Lolie Yu
Allison C. Grimes
Melissa P. Beauchemin
Lisa M. Klesges
George A. Tomlinson
Lillian Sung
author_facet L. Lee Dupuis
Emily Vettese
Catherine Aftandilian
Vibhuti Agarwal
Christina Baggott
Scott M. Bradfield
Nicole Crellin‐Parsons
David R. Freyer
Kara M. Kelly
Allison A. King
Wade Kyono
Ramamoorthy Nagasubramanian
Etan Orgel
Michael E. Roth
Farha Sherani
Lolie Yu
Allison C. Grimes
Melissa P. Beauchemin
Lisa M. Klesges
George A. Tomlinson
Lillian Sung
author_sort L. Lee Dupuis
collection DOAJ
description ABSTRACT Introduction Objective was to describe the association between baseline characteristics and the number of Symptom Screening in Pediatrics Tool (SSPedi) assessments completed over an 8‐week period. Methods This was a sub‐analysis of a cluster randomized controlled trial among 10 sites that were randomized to the intervention group. Participants were English‐ or Spanish‐speaking pediatric patients 8–18 years of age newly diagnosed with cancer. Participants were prompted to complete SSPedi three times weekly for 8 weeks. The outcome was the number of SSPedi assessments completed during the 8‐week period. Factors associated with the number of assessments were determined using mixed effects Poisson regression. Results At the 10 intervention sites, 216 patients were included in the analysis. Among these participants, 129 (59.7%) were male, 112 (51.9%) were white, and 83 (38.4%) were Hispanic. The number of SSPedi assessments was significantly higher for participants 11–14 years (rate ratio (RR) 1.13, 95% confidence interval (CI) 1.02–1.25) and 15–18 years (RR 1.15, 95% CI 1.04–1.27) compared to 8–10 years. Participants completed more SSPedi assessments if they were Asian compared to white (RR 1.27, 95% CI 1.10–1.46), non‐Hispanic compared to Hispanic (RR 1.15, 95% CI 1.04–1.28) and from families with a household income ≥$60,000 (RR 1.12, 95% CI 1.03–1.21). Participants completed fewer SSPedi assessments if they had solid tumors compared to leukemia (RR 0.91, 95% CI 0.84–0.99). Conclusion Adherence to three‐times weekly SSPedi varied by age, race, ethnicity, cancer diagnosis, and family income. This information may facilitate interventions to support routine symptom screening in clinical practice. Trial Registration: NCT04614662.
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spelling doaj-art-ec56c7bf2be049d6bf2449c437b8479b2025-08-20T03:35:36ZengWileyCancer Medicine2045-76342025-07-011414n/an/a10.1002/cam4.71053Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer PatientsL. Lee Dupuis0Emily Vettese1Catherine Aftandilian2Vibhuti Agarwal3Christina Baggott4Scott M. Bradfield5Nicole Crellin‐Parsons6David R. Freyer7Kara M. Kelly8Allison A. King9Wade Kyono10Ramamoorthy Nagasubramanian11Etan Orgel12Michael E. Roth13Farha Sherani14Lolie Yu15Allison C. Grimes16Melissa P. Beauchemin17Lisa M. Klesges18George A. Tomlinson19Lillian Sung20Program in Child Health Evaluative Sciences, the Hospital for Sick Children Toronto Ontario CanadaProgram in Child Health Evaluative Sciences, the Hospital for Sick Children Toronto Ontario CanadaDivision of Pediatric Hematology Oncology, Stem Cell Transplant and Regenerative Medicine, Stanford University Palo Alto California USANemours Children's Hospital Orlando Florida USADivision of Pediatric Hematology Oncology, Stem Cell Transplant and Regenerative Medicine, Stanford University Palo Alto California USANemours Children's Health Jacksonville Florida USAProgram in Child Health Evaluative Sciences, the Hospital for Sick Children Toronto Ontario CanadaCancer and Blood Disease Institute, Children's Hospital los Angeles Los Angeles California USADepartment of Pediatrics Roswell Park Comprehensive Cancer Center, University at Buffalo Jacobs School of Medicine and Biomedical Sciences Buffalo New York USADivision of Public Health Sciences Washington University School of Medicine St. Louis Missouri USAKapi'olani Medical Center for Women & Children Honolulu Hawaii USANemours Children's Hospital Orlando Florida USACancer and Blood Disease Institute, Children's Hospital los Angeles Los Angeles California USADepartment of Pediatrics The University of Texas MD Anderson Cancer Center Houston Texas USADriscoll Children's Hospital, Cancer and Blood Disorders Center and Texas A&M University Corpus Christi Texas USALouisiana State University Health Sciences Center/Children's Hospital New Orleans Louisiana USAPediatric Hematology Oncology, University of Texas Health Science Center at san Antonio San Antonio Texas USAColumbia University School of Nursing/Herbert Irving Cancer Center New York New York USADivision of Public Health Sciences Washington University School of Medicine St. Louis Missouri USADepartment of Medicine, Toronto General Hospital Toronto Ontario CanadaProgram in Child Health Evaluative Sciences, the Hospital for Sick Children Toronto Ontario CanadaABSTRACT Introduction Objective was to describe the association between baseline characteristics and the number of Symptom Screening in Pediatrics Tool (SSPedi) assessments completed over an 8‐week period. Methods This was a sub‐analysis of a cluster randomized controlled trial among 10 sites that were randomized to the intervention group. Participants were English‐ or Spanish‐speaking pediatric patients 8–18 years of age newly diagnosed with cancer. Participants were prompted to complete SSPedi three times weekly for 8 weeks. The outcome was the number of SSPedi assessments completed during the 8‐week period. Factors associated with the number of assessments were determined using mixed effects Poisson regression. Results At the 10 intervention sites, 216 patients were included in the analysis. Among these participants, 129 (59.7%) were male, 112 (51.9%) were white, and 83 (38.4%) were Hispanic. The number of SSPedi assessments was significantly higher for participants 11–14 years (rate ratio (RR) 1.13, 95% confidence interval (CI) 1.02–1.25) and 15–18 years (RR 1.15, 95% CI 1.04–1.27) compared to 8–10 years. Participants completed more SSPedi assessments if they were Asian compared to white (RR 1.27, 95% CI 1.10–1.46), non‐Hispanic compared to Hispanic (RR 1.15, 95% CI 1.04–1.28) and from families with a household income ≥$60,000 (RR 1.12, 95% CI 1.03–1.21). Participants completed fewer SSPedi assessments if they had solid tumors compared to leukemia (RR 0.91, 95% CI 0.84–0.99). Conclusion Adherence to three‐times weekly SSPedi varied by age, race, ethnicity, cancer diagnosis, and family income. This information may facilitate interventions to support routine symptom screening in clinical practice. Trial Registration: NCT04614662.https://doi.org/10.1002/cam4.71053adherenceoncologypediatricsymptom screening
spellingShingle L. Lee Dupuis
Emily Vettese
Catherine Aftandilian
Vibhuti Agarwal
Christina Baggott
Scott M. Bradfield
Nicole Crellin‐Parsons
David R. Freyer
Kara M. Kelly
Allison A. King
Wade Kyono
Ramamoorthy Nagasubramanian
Etan Orgel
Michael E. Roth
Farha Sherani
Lolie Yu
Allison C. Grimes
Melissa P. Beauchemin
Lisa M. Klesges
George A. Tomlinson
Lillian Sung
Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer Patients
Cancer Medicine
adherence
oncology
pediatric
symptom screening
title Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer Patients
title_full Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer Patients
title_fullStr Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer Patients
title_full_unstemmed Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer Patients
title_short Factors Associated With Self‐Report Symptom Screening Adherence in Pediatric Cancer Patients
title_sort factors associated with self report symptom screening adherence in pediatric cancer patients
topic adherence
oncology
pediatric
symptom screening
url https://doi.org/10.1002/cam4.71053
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