MYCN as an oncogene in pediatric brain tumors

MYCN as an oncogene in pediatric brain tumors

MYCN, or N-Myc, is a member of the MYC family of transcription factors, which plays a key role in tumor formation by regulating genes involved in proliferation, differentiation, and apoptosis. MYCN is essential for neural development, especially for the appropriate growth and differentiation of neur...

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Bibliographic Details
Main Authors: Adriana Fernandez Garcia, Jayden Jackson, Poorvi Iyer, Elissa G. Oliver, Kosuke Funato
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
MYCN
pediatric brain tumors
tumorigenesis
oncogene
neuro-oncology
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1584978/full
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