The role of systemic inflammation in the pathogenesis of hyperkinetic disorder

Hyperkinetic disorder (HD) is a common mental disorder in children and affects 5% of the population. In recent years, the important role of systemic inflammation in the pathogenesis of HD has been discussed. It is believed that the level of neutrophils, lymphocytes, platelets and monocytes, as well...

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Main Authors: Rauf F. Gasanov, Igor V. Makarov, Daria A. Emelina, Ilya V. Kravchenko, Ekaterina S. Prokhorenko
Format: Article
Language:Russian
Published: Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2024-04-01
Series:Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
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Online Access:https://www.bekhterevreview.com/jour/article/view/1167
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author Rauf F. Gasanov
Igor V. Makarov
Daria A. Emelina
Ilya V. Kravchenko
Ekaterina S. Prokhorenko
author_facet Rauf F. Gasanov
Igor V. Makarov
Daria A. Emelina
Ilya V. Kravchenko
Ekaterina S. Prokhorenko
author_sort Rauf F. Gasanov
collection DOAJ
description Hyperkinetic disorder (HD) is a common mental disorder in children and affects 5% of the population. In recent years, the important role of systemic inflammation in the pathogenesis of HD has been discussed. It is believed that the level of neutrophils, lymphocytes, platelets and monocytes, as well as their ratios, can serve as markers of systemic inflammation in HD. However, the question of the specificity of the data obtained remains open due to insufficient data. The specificity of markers of neuroinflammation and systemic inflammation, levels of hyperkinetic disorder remains insufficiently studied, which requires clarification in future studies with the exclusion of background residual organic pathology of the brain, inflammatory and autoimmune diseases in comparison not only with a group of healthy controls, but also with a group of patients with other mental disorders.
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institution Kabale University
issn 2313-7053
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language Russian
publishDate 2024-04-01
publisher Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
record_format Article
series Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
spelling doaj-art-ec4d73afbfcd44349e3efd49b89dfb372025-08-20T03:58:55ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2024-04-010010.31363/2313-7053-2025-3-1088610The role of systemic inflammation in the pathogenesis of hyperkinetic disorderRauf F. Gasanov0Igor V. Makarov1Daria A. Emelina2Ilya V. Kravchenko3Ekaterina S. Prokhorenko4V.M. Bekhterev National research medical center for psychiatry and neurologyV.M. Bekhterev National research medical center for psychiatry and neurologyV.M. Bekhterev National research medical center for psychiatry and neurologyV.M. Bekhterev National research medical center for psychiatry and neurologyV.M. Bekhterev National research medical center for psychiatry and neurologyHyperkinetic disorder (HD) is a common mental disorder in children and affects 5% of the population. In recent years, the important role of systemic inflammation in the pathogenesis of HD has been discussed. It is believed that the level of neutrophils, lymphocytes, platelets and monocytes, as well as their ratios, can serve as markers of systemic inflammation in HD. However, the question of the specificity of the data obtained remains open due to insufficient data. The specificity of markers of neuroinflammation and systemic inflammation, levels of hyperkinetic disorder remains insufficiently studied, which requires clarification in future studies with the exclusion of background residual organic pathology of the brain, inflammatory and autoimmune diseases in comparison not only with a group of healthy controls, but also with a group of patients with other mental disorders.https://www.bekhterevreview.com/jour/article/view/1167hyperkinetic disordersystemic inflammationinterleukinscellular ratiodepressioninflammationbiomarker
spellingShingle Rauf F. Gasanov
Igor V. Makarov
Daria A. Emelina
Ilya V. Kravchenko
Ekaterina S. Prokhorenko
The role of systemic inflammation in the pathogenesis of hyperkinetic disorder
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
hyperkinetic disorder
systemic inflammation
interleukins
cellular ratio
depression
inflammation
biomarker
title The role of systemic inflammation in the pathogenesis of hyperkinetic disorder
title_full The role of systemic inflammation in the pathogenesis of hyperkinetic disorder
title_fullStr The role of systemic inflammation in the pathogenesis of hyperkinetic disorder
title_full_unstemmed The role of systemic inflammation in the pathogenesis of hyperkinetic disorder
title_short The role of systemic inflammation in the pathogenesis of hyperkinetic disorder
title_sort role of systemic inflammation in the pathogenesis of hyperkinetic disorder
topic hyperkinetic disorder
systemic inflammation
interleukins
cellular ratio
depression
inflammation
biomarker
url https://www.bekhterevreview.com/jour/article/view/1167
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