A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging.

A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging.

Cdc42 is critical in a myriad of cellular morphogenic processes, requiring precisely regulated activation dynamics to affect specific cellular events. To facilitate direct observations of Cdc42 activation in live cells, we developed and validated a new biosensor of Cdc42 activation. The biosensor is...

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Bibliographic Details
Main Authors: Samer Hanna, Veronika Miskolci, Dianne Cox, Louis Hodgson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096469&type=printable
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