Quantifying the impact of unmeasured confounding in observational studies with the E value

The E value method deals with unmeasured confounding, a key source of bias in observational studies. The E value method is described and its use is shown in a worked example of a meta-analysis examining the association between the use of antidepressants in pregnancy and the risk of miscarriage.

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Main Authors: Irene Petersen, Vera Ehrenstein, Henrik Støvring, Tobias Gaster, Christine Marie Eggertsen
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:BMJ Medicine
Online Access:https://bmjmedicine.bmj.com/content/2/1/e000366.full
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author Irene Petersen
Vera Ehrenstein
Henrik Støvring
Tobias Gaster
Christine Marie Eggertsen
author_facet Irene Petersen
Vera Ehrenstein
Henrik Støvring
Tobias Gaster
Christine Marie Eggertsen
author_sort Irene Petersen
collection DOAJ
description The E value method deals with unmeasured confounding, a key source of bias in observational studies. The E value method is described and its use is shown in a worked example of a meta-analysis examining the association between the use of antidepressants in pregnancy and the risk of miscarriage.
format Article
id doaj-art-ec410601d2de4ed7a0d02ec8d9733e18
institution OA Journals
issn 2754-0413
language English
publishDate 2023-10-01
publisher BMJ Publishing Group
record_format Article
series BMJ Medicine
spelling doaj-art-ec410601d2de4ed7a0d02ec8d9733e182025-08-20T02:30:35ZengBMJ Publishing GroupBMJ Medicine2754-04132023-10-012110.1136/bmjmed-2022-000366Quantifying the impact of unmeasured confounding in observational studies with the E valueIrene Petersen0Vera Ehrenstein1Henrik Støvring2Tobias Gaster3Christine Marie Eggertsen43 Department of Clinical Epidemiology, Aarhus University & Aarhus University Hospital, Aarhus, Denmark3 Department of Clinical Epidemiology, Aarhus University & Aarhus University Hospital, Aarhus, DenmarkSteno Diabetes Centre Aarhus, Aarhus, DenmarkAarhus University, Aarhus, DenmarkAarhus University, Aarhus, DenmarkThe E value method deals with unmeasured confounding, a key source of bias in observational studies. The E value method is described and its use is shown in a worked example of a meta-analysis examining the association between the use of antidepressants in pregnancy and the risk of miscarriage.https://bmjmedicine.bmj.com/content/2/1/e000366.full
spellingShingle Irene Petersen
Vera Ehrenstein
Henrik Støvring
Tobias Gaster
Christine Marie Eggertsen
Quantifying the impact of unmeasured confounding in observational studies with the E value
BMJ Medicine
title Quantifying the impact of unmeasured confounding in observational studies with the E value
title_full Quantifying the impact of unmeasured confounding in observational studies with the E value
title_fullStr Quantifying the impact of unmeasured confounding in observational studies with the E value
title_full_unstemmed Quantifying the impact of unmeasured confounding in observational studies with the E value
title_short Quantifying the impact of unmeasured confounding in observational studies with the E value
title_sort quantifying the impact of unmeasured confounding in observational studies with the e value
url https://bmjmedicine.bmj.com/content/2/1/e000366.full
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AT tobiasgaster quantifyingtheimpactofunmeasuredconfoundinginobservationalstudieswiththeevalue
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