Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusion
Background To treat symptoms brought on by a large, recurring malignant pleural effusion, chemical pleurodesis is recommended. Before pleurodesis, a drain is left in the pleural space until the pleural fluid collection stops. As little as 50 ml of pleural fluid can be found using chest ultrasonograp...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-01-01
|
| Series: | Egyptian Journal of Chest Disease and Tuberculosis |
| Subjects: | |
| Online Access: | https://doi.org/10.4103/ecdt.ecdt_38_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849773945594576896 |
|---|---|
| author | Mohamed S. Sadek Tarek S. Essawy Elsayed A. Taha Marwa E. Elnaggar |
| author_facet | Mohamed S. Sadek Tarek S. Essawy Elsayed A. Taha Marwa E. Elnaggar |
| author_sort | Mohamed S. Sadek |
| collection | DOAJ |
| description | Background To treat symptoms brought on by a large, recurring malignant pleural effusion, chemical pleurodesis is recommended. Before pleurodesis, a drain is left in the pleural space until the pleural fluid collection stops. As little as 50 ml of pleural fluid can be found using chest ultrasonography, which can also verify the pleural surfaces’ conjunction, a sign of successful pleurodesis. Patients and methods Thirty patients with malignant pleural effusion had intercostal tube insertion as part of this interventional trial. Before the sclerosing drug was injected, transthoracic ultrasonography was used to evaluate each case to see whether the sliding sign was present. A month later, a follow-up transthoracic ultrasound was performed to evaluate the sliding sign, which indicates whether the pleurodesis was successful or not. Results The mean age of participants was 60 ± 12 years, with slightly more males (53.3%, n=16) than females (46.7%, n=14). Two-thirds (66.7%) reported chest pain, while half of the patients (50%) had complained of cough. The majority (76.7%, n=23) presented with pleural nodules. Every participant (100%) demonstrated the presence of both effusion and collapse in the computed tomography images. Most of the cases (63.3%, n=19) were treated with bleomycin during pleurodesis. All patients (100%) demonstrated the presence of the sliding sign before pleurodesis with significant absence after the procedure (P<0.001). 24 out of the 30 (80%) patients experienced successful outcomes. Conclusions Because thoracic ultrasonography may identify the lack of pleural sliding, it can be used to evaluate the success of pleurodesis. Furthermore, the results of pleurodesis were further confirmed by computed tomography scans and chest radiography, which completed the assessment by indicating the presence or absence of effusion and collapse. |
| format | Article |
| id | doaj-art-ec3bc8c953304d73b34f7ead47b7bc9f |
| institution | DOAJ |
| issn | 0422-7638 2090-9950 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Egyptian Journal of Chest Disease and Tuberculosis |
| spelling | doaj-art-ec3bc8c953304d73b34f7ead47b7bc9f2025-08-20T03:01:54ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382090-99502025-01-01741374410.4103/ecdt.ecdt_38_24Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusionMohamed S. SadekTarek S. EssawyElsayed A. TahaMarwa E. ElnaggarBackground To treat symptoms brought on by a large, recurring malignant pleural effusion, chemical pleurodesis is recommended. Before pleurodesis, a drain is left in the pleural space until the pleural fluid collection stops. As little as 50 ml of pleural fluid can be found using chest ultrasonography, which can also verify the pleural surfaces’ conjunction, a sign of successful pleurodesis. Patients and methods Thirty patients with malignant pleural effusion had intercostal tube insertion as part of this interventional trial. Before the sclerosing drug was injected, transthoracic ultrasonography was used to evaluate each case to see whether the sliding sign was present. A month later, a follow-up transthoracic ultrasound was performed to evaluate the sliding sign, which indicates whether the pleurodesis was successful or not. Results The mean age of participants was 60 ± 12 years, with slightly more males (53.3%, n=16) than females (46.7%, n=14). Two-thirds (66.7%) reported chest pain, while half of the patients (50%) had complained of cough. The majority (76.7%, n=23) presented with pleural nodules. Every participant (100%) demonstrated the presence of both effusion and collapse in the computed tomography images. Most of the cases (63.3%, n=19) were treated with bleomycin during pleurodesis. All patients (100%) demonstrated the presence of the sliding sign before pleurodesis with significant absence after the procedure (P<0.001). 24 out of the 30 (80%) patients experienced successful outcomes. Conclusions Because thoracic ultrasonography may identify the lack of pleural sliding, it can be used to evaluate the success of pleurodesis. Furthermore, the results of pleurodesis were further confirmed by computed tomography scans and chest radiography, which completed the assessment by indicating the presence or absence of effusion and collapse.https://doi.org/10.4103/ecdt.ecdt_38_24chest ultrasoundmalignant pleural effusionpleurodesissliding sign |
| spellingShingle | Mohamed S. Sadek Tarek S. Essawy Elsayed A. Taha Marwa E. Elnaggar Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusion Egyptian Journal of Chest Disease and Tuberculosis chest ultrasound malignant pleural effusion pleurodesis sliding sign |
| title | Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusion |
| title_full | Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusion |
| title_fullStr | Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusion |
| title_full_unstemmed | Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusion |
| title_short | Different radiologic procedures to evaluate the success of Pleurodesis in patients with malignant pleural effusion |
| title_sort | different radiologic procedures to evaluate the success of pleurodesis in patients with malignant pleural effusion |
| topic | chest ultrasound malignant pleural effusion pleurodesis sliding sign |
| url | https://doi.org/10.4103/ecdt.ecdt_38_24 |
| work_keys_str_mv | AT mohamedssadek differentradiologicprocedurestoevaluatethesuccessofpleurodesisinpatientswithmalignantpleuraleffusion AT tareksessawy differentradiologicprocedurestoevaluatethesuccessofpleurodesisinpatientswithmalignantpleuraleffusion AT elsayedataha differentradiologicprocedurestoevaluatethesuccessofpleurodesisinpatientswithmalignantpleuraleffusion AT marwaeelnaggar differentradiologicprocedurestoevaluatethesuccessofpleurodesisinpatientswithmalignantpleuraleffusion |