Assessment of Herbal Medicament in Treatment of Oral Lichen Planus Lesion

Objectives: Comparative assessment of effectiveness of topical coconut cream, pomegranate, and Tacrolimus 0.1% in treatment of oral lichen planus (OLP) lesion. Materials and Methods: Thirty patients with histologically confirmed symptomatic OLP exhibiting gingival manifestation were included in this...

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Main Authors: Ravinder Singh, Cheena Singh, Nidhi Aggarwal, Sushruth Nayak, Prachi Nayak, Veenu Dahiya, K Saidath
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_709_24
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author Ravinder Singh
Cheena Singh
Nidhi Aggarwal
Sushruth Nayak
Prachi Nayak
Veenu Dahiya
K Saidath
author_facet Ravinder Singh
Cheena Singh
Nidhi Aggarwal
Sushruth Nayak
Prachi Nayak
Veenu Dahiya
K Saidath
author_sort Ravinder Singh
collection DOAJ
description Objectives: Comparative assessment of effectiveness of topical coconut cream, pomegranate, and Tacrolimus 0.1% in treatment of oral lichen planus (OLP) lesion. Materials and Methods: Thirty patients with histologically confirmed symptomatic OLP exhibiting gingival manifestation were included in this investigation. Group A received topical coconut cream, Group B received pomegranate, and Group C received topical tacrolimus 0.1% ointment. The participants were split into these three groups. For six months, the participants were told to use topical medicines twice a day. For the purpose of monitoring any relapse, the patients were summoned back one, three, and six months after the therapy was stopped. Result: Both the extent of the lesion and the burning sensation/pain were significantly reduced in all groups of participants. Conclusion: The size of the lesion and the burning feeling were significantly reduced when using coconut cream. For the treatment of OLP, tacrolimus, coconut cream, and pomegranates are viable topical pharmaceutical alternatives.
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institution Kabale University
issn 0976-4879
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language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-ec3a06d0cc454773a3ad8a3a237971c22025-01-12T14:11:49ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3224S322610.4103/jpbs.jpbs_709_24Assessment of Herbal Medicament in Treatment of Oral Lichen Planus LesionRavinder SinghCheena SinghNidhi AggarwalSushruth NayakPrachi NayakVeenu DahiyaK SaidathObjectives: Comparative assessment of effectiveness of topical coconut cream, pomegranate, and Tacrolimus 0.1% in treatment of oral lichen planus (OLP) lesion. Materials and Methods: Thirty patients with histologically confirmed symptomatic OLP exhibiting gingival manifestation were included in this investigation. Group A received topical coconut cream, Group B received pomegranate, and Group C received topical tacrolimus 0.1% ointment. The participants were split into these three groups. For six months, the participants were told to use topical medicines twice a day. For the purpose of monitoring any relapse, the patients were summoned back one, three, and six months after the therapy was stopped. Result: Both the extent of the lesion and the burning sensation/pain were significantly reduced in all groups of participants. Conclusion: The size of the lesion and the burning feeling were significantly reduced when using coconut cream. For the treatment of OLP, tacrolimus, coconut cream, and pomegranates are viable topical pharmaceutical alternatives.https://journals.lww.com/10.4103/jpbs.jpbs_709_24coconut creamdesquamative gingivitisoral lichen planustacrolimus
spellingShingle Ravinder Singh
Cheena Singh
Nidhi Aggarwal
Sushruth Nayak
Prachi Nayak
Veenu Dahiya
K Saidath
Assessment of Herbal Medicament in Treatment of Oral Lichen Planus Lesion
Journal of Pharmacy and Bioallied Sciences
coconut cream
desquamative gingivitis
oral lichen planus
tacrolimus
title Assessment of Herbal Medicament in Treatment of Oral Lichen Planus Lesion
title_full Assessment of Herbal Medicament in Treatment of Oral Lichen Planus Lesion
title_fullStr Assessment of Herbal Medicament in Treatment of Oral Lichen Planus Lesion
title_full_unstemmed Assessment of Herbal Medicament in Treatment of Oral Lichen Planus Lesion
title_short Assessment of Herbal Medicament in Treatment of Oral Lichen Planus Lesion
title_sort assessment of herbal medicament in treatment of oral lichen planus lesion
topic coconut cream
desquamative gingivitis
oral lichen planus
tacrolimus
url https://journals.lww.com/10.4103/jpbs.jpbs_709_24
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