Seeing beyond the norm: Unveiling ocular complications with atypical antipsychotics

Psychotropic medications, particularly antipsychotics, are known to elicit various adverse effects, with ocular complications being underreported yet significant. This case series presents three instances where atypical antipsychotics, namely Risperidone, Cariprazine, and Olanzapine, led to ocular d...

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Main Authors: Akansha Bhardwaj, Adarsh Bhardwaj, Bhumika, Ashu Sirowa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Industrial Psychiatry Journal
Subjects:
Online Access:https://journals.lww.com/10.4103/ipj.ipj_134_24
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author Akansha Bhardwaj
Adarsh Bhardwaj
Bhumika
Ashu Sirowa
author_facet Akansha Bhardwaj
Adarsh Bhardwaj
Bhumika
Ashu Sirowa
author_sort Akansha Bhardwaj
collection DOAJ
description Psychotropic medications, particularly antipsychotics, are known to elicit various adverse effects, with ocular complications being underreported yet significant. This case series presents three instances where atypical antipsychotics, namely Risperidone, Cariprazine, and Olanzapine, led to ocular dystonias and nystagmus. These adverse effects occurred at relatively low doses, highlighting the need for vigilant monitoring even with second-generation antipsychotics. Case descriptions delineate patients experiencing acute dystonic reactions and nystagmus following initiation or dose adjustment of atypical antipsychotics, leading to upward deviation of the eyes, involuntary movements, and nystagmus. Prompt recognition and management were crucial, with cessation of the offending medication resulting in symptom remission and subsequent stabilization with alternative treatments. Factors contributing to these adverse effects, such as dopamine receptor blockade and individual susceptibility, are explored, emphasizing the importance of comprehensive evaluation and open patient–physician communication. The present case series underscores the necessity of vigilant monitoring for ocular adverse effects, even with atypical antipsychotics, given their potential to induce acute dystonias and nystagmus. The presented cases advocate for heightened awareness among clinicians to promptly recognize and manage such rare complications, ensuring optimal patient care and treatment outcomes.
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spelling doaj-art-ec39df2187a4460c888fdb181152a9622025-08-20T02:54:25ZengWolters Kluwer Medknow PublicationsIndustrial Psychiatry Journal0972-67480976-27952024-12-0133240941310.4103/ipj.ipj_134_24Seeing beyond the norm: Unveiling ocular complications with atypical antipsychoticsAkansha BhardwajAdarsh BhardwajBhumikaAshu SirowaPsychotropic medications, particularly antipsychotics, are known to elicit various adverse effects, with ocular complications being underreported yet significant. This case series presents three instances where atypical antipsychotics, namely Risperidone, Cariprazine, and Olanzapine, led to ocular dystonias and nystagmus. These adverse effects occurred at relatively low doses, highlighting the need for vigilant monitoring even with second-generation antipsychotics. Case descriptions delineate patients experiencing acute dystonic reactions and nystagmus following initiation or dose adjustment of atypical antipsychotics, leading to upward deviation of the eyes, involuntary movements, and nystagmus. Prompt recognition and management were crucial, with cessation of the offending medication resulting in symptom remission and subsequent stabilization with alternative treatments. Factors contributing to these adverse effects, such as dopamine receptor blockade and individual susceptibility, are explored, emphasizing the importance of comprehensive evaluation and open patient–physician communication. The present case series underscores the necessity of vigilant monitoring for ocular adverse effects, even with atypical antipsychotics, given their potential to induce acute dystonias and nystagmus. The presented cases advocate for heightened awareness among clinicians to promptly recognize and manage such rare complications, ensuring optimal patient care and treatment outcomes.https://journals.lww.com/10.4103/ipj.ipj_134_24acute dystoniaeye complicationsnystagmusocular side effectsoculogyric crisis
spellingShingle Akansha Bhardwaj
Adarsh Bhardwaj
Bhumika
Ashu Sirowa
Seeing beyond the norm: Unveiling ocular complications with atypical antipsychotics
Industrial Psychiatry Journal
acute dystonia
eye complications
nystagmus
ocular side effects
oculogyric crisis
title Seeing beyond the norm: Unveiling ocular complications with atypical antipsychotics
title_full Seeing beyond the norm: Unveiling ocular complications with atypical antipsychotics
title_fullStr Seeing beyond the norm: Unveiling ocular complications with atypical antipsychotics
title_full_unstemmed Seeing beyond the norm: Unveiling ocular complications with atypical antipsychotics
title_short Seeing beyond the norm: Unveiling ocular complications with atypical antipsychotics
title_sort seeing beyond the norm unveiling ocular complications with atypical antipsychotics
topic acute dystonia
eye complications
nystagmus
ocular side effects
oculogyric crisis
url https://journals.lww.com/10.4103/ipj.ipj_134_24
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