PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCER

Abstract: lung cancer takes the second place in the general structure of incidence of malignant neoplasms in Russia. The diagnosis of a local or metastatic non small cells lung cancer (NSCLC) serves the indication to carrying out the 1st line chemotherapy. In case of progressing against or after the...

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Main Author: A. U. Kulikov
Format: Article
Language:Russian
Published: IRBIS LLC 2015-03-01
Series:Фармакоэкономика
Subjects:
Online Access:https://www.pharmacoeconomics.ru/jour/article/view/35
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author A. U. Kulikov
author_facet A. U. Kulikov
author_sort A. U. Kulikov
collection DOAJ
description Abstract: lung cancer takes the second place in the general structure of incidence of malignant neoplasms in Russia. The diagnosis of a local or metastatic non small cells lung cancer (NSCLC) serves the indication to carrying out the 1st line chemotherapy. In case of progressing against or after the 1st line chemotherapy the 2nd line of treatment of NSCLC is carried out. As the 2nd line of monotherapy of NSCLC there are used docetaxel or pemetrexed and representatives of a class of target oral medicines – gefitinib and erlotinib. This article presents results of comparative pharmacoeconomical estimation of this medicines in real modern health care system of Russian Federation. According to the obtained results application of erlotinib as the 2nd line therapy of patients with local or metastatic NSCLC is more preferable than docetaxel, pemetrexed or gefitinibfrom the economic point of view.
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2070-4933
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series Фармакоэкономика
spelling doaj-art-ec38d392a6dd4d9db01d5560ba524cc02025-08-20T03:19:23ZrusIRBIS LLCФармакоэкономика2070-49092070-49332015-03-015381229PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCERA. U. Kulikov0Laboratory of pharmacoeconomic researches of the First Moscow State Medical University named after I.M. Sechenov, MoscowAbstract: lung cancer takes the second place in the general structure of incidence of malignant neoplasms in Russia. The diagnosis of a local or metastatic non small cells lung cancer (NSCLC) serves the indication to carrying out the 1st line chemotherapy. In case of progressing against or after the 1st line chemotherapy the 2nd line of treatment of NSCLC is carried out. As the 2nd line of monotherapy of NSCLC there are used docetaxel or pemetrexed and representatives of a class of target oral medicines – gefitinib and erlotinib. This article presents results of comparative pharmacoeconomical estimation of this medicines in real modern health care system of Russian Federation. According to the obtained results application of erlotinib as the 2nd line therapy of patients with local or metastatic NSCLC is more preferable than docetaxel, pemetrexed or gefitinibfrom the economic point of view.https://www.pharmacoeconomics.ru/jour/article/view/35non small cells lung cancererlotinibpemetrexedgefitinibdocetaxel«cost-effectiveness»«cost-utility»
spellingShingle A. U. Kulikov
PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCER
Фармакоэкономика
non small cells lung cancer
erlotinib
pemetrexed
gefitinib
docetaxel
«cost-effectiveness»
«cost-utility»
title PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCER
title_full PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCER
title_fullStr PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCER
title_full_unstemmed PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCER
title_short PHARMACOECONOMIC EVALUATION OF THE MEDICINAL PRODUCTS ERLOTINIB, DOCETAXEL, PEMETREXED AND GEFITINIB IN THE SECOND-LINE TREATMENT OF LOCALLY-ADVANCED OR METASTATIC NON-SMALL-CELL LUNG CANCER
title_sort pharmacoeconomic evaluation of the medicinal products erlotinib docetaxel pemetrexed and gefitinib in the second line treatment of locally advanced or metastatic non small cell lung cancer
topic non small cells lung cancer
erlotinib
pemetrexed
gefitinib
docetaxel
«cost-effectiveness»
«cost-utility»
url https://www.pharmacoeconomics.ru/jour/article/view/35
work_keys_str_mv AT aukulikov pharmacoeconomicevaluationofthemedicinalproductserlotinibdocetaxelpemetrexedandgefitinibinthesecondlinetreatmentoflocallyadvancedormetastaticnonsmallcelllungcancer