Musculoskeletal Manifestations of Dengue Fever
Introduction: Dengue fever is a multisystem disease that can present with varying severity. With the increasing incidence of dengue-associated morbidity and mortality globally, atypical manifestations are now included in the case definition of severe dengue. Musculoskeletal involvement in dengue ran...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | APIK Journal of Internal Medicine |
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| Online Access: | https://journals.lww.com/10.4103/ajim.ajim_111_23 |
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| author | Vasantha Kamath B. L. Avinash Shreyashi Ganguly Kushal Markanday |
| author_facet | Vasantha Kamath B. L. Avinash Shreyashi Ganguly Kushal Markanday |
| author_sort | Vasantha Kamath |
| collection | DOAJ |
| description | Introduction:
Dengue fever is a multisystem disease that can present with varying severity. With the increasing incidence of dengue-associated morbidity and mortality globally, atypical manifestations are now included in the case definition of severe dengue. Musculoskeletal involvement in dengue ranges from troubling myalgia to life-threatening rhabdomyolysis. However, it is often underreported and underdiagnosed due to a lack of awareness. Hence, this study was undertaken to evaluate dengue patients for specific musculoskeletal presentation.
Materials and Methods:
A prospective study was undertaken between September 2020 and August 2022, with 200 adult dengue patients presenting to the outpatient department or hospitalized in patient department (IPD) at a rural tertiary care hospital. They were assessed, the diagnosis was confirmed with serology, and they were subjected to thorough clinical examination and relevant laboratory studies as was necessary to establish musculoskeletal features of dengue.
Results:
Ninety-five percent of patients had myalgia, 13.5% of patients had myositis, and 14% of patients were found to have hypokalemia; however, only 2.5% of patients developed hypokalemic periodic paralysis. Seventy-three percent of cases reported arthralgia, while none of the cases reported arthritis or rhabdomyolysis.
Conclusion:
Musculoskeletal manifestations of dengue are common, although they are underreported in medical literature. However, many patients with dengue illness presenting with myalgia and progressing to myositis may not have been noticed in practice due to a lack of awareness. Hence, developing awareness and early recognition of this treatable manifestation of dengue become necessary. |
| format | Article |
| id | doaj-art-ec30124963f4485e9c83992c02353e56 |
| institution | Kabale University |
| issn | 2666-1802 2666-1810 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | APIK Journal of Internal Medicine |
| spelling | doaj-art-ec30124963f4485e9c83992c02353e562025-01-07T07:14:00ZengWolters Kluwer Medknow PublicationsAPIK Journal of Internal Medicine2666-18022666-18102025-01-01131394410.4103/ajim.ajim_111_23Musculoskeletal Manifestations of Dengue FeverVasantha KamathB. L. AvinashShreyashi GangulyKushal MarkandayIntroduction: Dengue fever is a multisystem disease that can present with varying severity. With the increasing incidence of dengue-associated morbidity and mortality globally, atypical manifestations are now included in the case definition of severe dengue. Musculoskeletal involvement in dengue ranges from troubling myalgia to life-threatening rhabdomyolysis. However, it is often underreported and underdiagnosed due to a lack of awareness. Hence, this study was undertaken to evaluate dengue patients for specific musculoskeletal presentation. Materials and Methods: A prospective study was undertaken between September 2020 and August 2022, with 200 adult dengue patients presenting to the outpatient department or hospitalized in patient department (IPD) at a rural tertiary care hospital. They were assessed, the diagnosis was confirmed with serology, and they were subjected to thorough clinical examination and relevant laboratory studies as was necessary to establish musculoskeletal features of dengue. Results: Ninety-five percent of patients had myalgia, 13.5% of patients had myositis, and 14% of patients were found to have hypokalemia; however, only 2.5% of patients developed hypokalemic periodic paralysis. Seventy-three percent of cases reported arthralgia, while none of the cases reported arthritis or rhabdomyolysis. Conclusion: Musculoskeletal manifestations of dengue are common, although they are underreported in medical literature. However, many patients with dengue illness presenting with myalgia and progressing to myositis may not have been noticed in practice due to a lack of awareness. Hence, developing awareness and early recognition of this treatable manifestation of dengue become necessary.https://journals.lww.com/10.4103/ajim.ajim_111_23hypokalemic periodic paralysismusculoskeletal manifestations of denguemyositissevere dengue |
| spellingShingle | Vasantha Kamath B. L. Avinash Shreyashi Ganguly Kushal Markanday Musculoskeletal Manifestations of Dengue Fever APIK Journal of Internal Medicine hypokalemic periodic paralysis musculoskeletal manifestations of dengue myositis severe dengue |
| title | Musculoskeletal Manifestations of Dengue Fever |
| title_full | Musculoskeletal Manifestations of Dengue Fever |
| title_fullStr | Musculoskeletal Manifestations of Dengue Fever |
| title_full_unstemmed | Musculoskeletal Manifestations of Dengue Fever |
| title_short | Musculoskeletal Manifestations of Dengue Fever |
| title_sort | musculoskeletal manifestations of dengue fever |
| topic | hypokalemic periodic paralysis musculoskeletal manifestations of dengue myositis severe dengue |
| url | https://journals.lww.com/10.4103/ajim.ajim_111_23 |
| work_keys_str_mv | AT vasanthakamath musculoskeletalmanifestationsofdenguefever AT blavinash musculoskeletalmanifestationsofdenguefever AT shreyashiganguly musculoskeletalmanifestationsofdenguefever AT kushalmarkanday musculoskeletalmanifestationsofdenguefever |