Design of AgNPs loaded γ-PGA chitosan conduits with superior antibacterial activity and nerve repair properties

Design of AgNPs loaded γ-PGA chitosan conduits with superior antibacterial activity and nerve repair properties

To address the challenge of infections during peripheral nerve defect repair, this study introduces a γ-polyglutamic acid (γ-PGA) polymers designed to encapsulate silver nanoparticles (AgNPs). The AgNPs loaded γ-PGA polymers is applied as a coating on both the inner and outer surfaces of chitosan ne...

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Bibliographic Details
Main Authors: Yang Qu, Yinglei Ma, Heng An, Meng Zhang, Haoran Jiang, Bohan Xing, Bojiang Wang, Yanqun Liu, Yongqiang Wen, Peixun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
γ-PGA
AgNPs
chitosan
antibacterial activity
peripheral nerve repair
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1561330/full
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