Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants
In hereditary retinal diseases photoreceptors progressively degenerate, often causing blindness without therapy being available. Newly developed subretinal implants can substitute functions of photoreceptors. Retina implant extraocular surgical technique relies strongly on cochlear-implant know-how....
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2015/842518 |
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| author | Assen Koitschev Katarina Stingl Karl Ulrich Bartz-Schmidt Angelika Braun Florian Gekeler Udo Greppmaier Helmut Sachs Tobias Peters Barbara Wilhelm Eberhart Zrenner Dorothea Besch |
| author_facet | Assen Koitschev Katarina Stingl Karl Ulrich Bartz-Schmidt Angelika Braun Florian Gekeler Udo Greppmaier Helmut Sachs Tobias Peters Barbara Wilhelm Eberhart Zrenner Dorothea Besch |
| author_sort | Assen Koitschev |
| collection | DOAJ |
| description | In hereditary retinal diseases photoreceptors progressively degenerate, often causing blindness without therapy being available. Newly developed subretinal implants can substitute functions of photoreceptors. Retina implant extraocular surgical technique relies strongly on cochlear-implant know-how. However, a completely new surgical approach providing safe handling of the photosensor array had to be developed. The Retina Implant Alpha IMS consisting of a subretinal microphotodiode array and cable linked to a cochlear-implant-like ceramic housing was introduced via a retroauricular incision through a subperiosteal tunnel above the zygoma into the orbit using a specially designed trocar. Implant housing was fixed in a bony bed within a tight subperiosteal pocket in all patients. Primary outcomes were patient short term safety as well as effectiveness. Nine patients participated in the first part of the multicenter trial and received the subretinal visual implant in one eye. In all cases microphotodiode array pull-through procedure and stable positioning were possible without affecting the device function. No intraoperative complications were encountered. The minimally invasive suprazygomatic tunneling technique for the sensor unit as well as a subperiosteal pocket fixation of the implant housing provides a safe extraocular implantation approach of a subretinal device with a transcutaneous extracorporeal power supply. |
| format | Article |
| id | doaj-art-ec26fbd489a6482ca51500de265262f3 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-ec26fbd489a6482ca51500de265262f32025-02-03T01:24:22ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/842518842518Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-ImplantsAssen Koitschev0Katarina Stingl1Karl Ulrich Bartz-Schmidt2Angelika Braun3Florian Gekeler4Udo Greppmaier5Helmut Sachs6Tobias Peters7Barbara Wilhelm8Eberhart Zrenner9Dorothea Besch10Klinikum Stuttgart-Olgahospital, ORL-Department, Pediatric Otorhinolaryngology and Otology, Kriegsbergstraße 62, 70176 Stuttgart, GermanyCenter for Ophthalmology, University of Tübingen, Schleichstraße 12-16, 72076 Tübingen, GermanyCenter for Ophthalmology, University of Tübingen, Schleichstraße 12-16, 72076 Tübingen, GermanyRetina Implant AG, Gerhard-Kindler-Straße 8, 72770 Reutlingen, GermanyCenter for Ophthalmology, University of Tübingen, Schleichstraße 12-16, 72076 Tübingen, GermanyRetina Implant AG, Gerhard-Kindler-Straße 8, 72770 Reutlingen, GermanyKlinikum Dresden Friedrichstadt, University Teaching Hospital, Eye Clinic, Friedrichstraße 41, 01067 Dresden, GermanySTZ Eyetrial, Center for Ophthalmology, University of Tübingen, Schleichstraße 12-16, 72076 Tübingen, GermanySTZ Eyetrial, Center for Ophthalmology, University of Tübingen, Schleichstraße 12-16, 72076 Tübingen, GermanyCenter for Ophthalmology, University of Tübingen, Schleichstraße 12-16, 72076 Tübingen, GermanyCenter for Ophthalmology, University of Tübingen, Schleichstraße 12-16, 72076 Tübingen, GermanyIn hereditary retinal diseases photoreceptors progressively degenerate, often causing blindness without therapy being available. Newly developed subretinal implants can substitute functions of photoreceptors. Retina implant extraocular surgical technique relies strongly on cochlear-implant know-how. However, a completely new surgical approach providing safe handling of the photosensor array had to be developed. The Retina Implant Alpha IMS consisting of a subretinal microphotodiode array and cable linked to a cochlear-implant-like ceramic housing was introduced via a retroauricular incision through a subperiosteal tunnel above the zygoma into the orbit using a specially designed trocar. Implant housing was fixed in a bony bed within a tight subperiosteal pocket in all patients. Primary outcomes were patient short term safety as well as effectiveness. Nine patients participated in the first part of the multicenter trial and received the subretinal visual implant in one eye. In all cases microphotodiode array pull-through procedure and stable positioning were possible without affecting the device function. No intraoperative complications were encountered. The minimally invasive suprazygomatic tunneling technique for the sensor unit as well as a subperiosteal pocket fixation of the implant housing provides a safe extraocular implantation approach of a subretinal device with a transcutaneous extracorporeal power supply.http://dx.doi.org/10.1155/2015/842518 |
| spellingShingle | Assen Koitschev Katarina Stingl Karl Ulrich Bartz-Schmidt Angelika Braun Florian Gekeler Udo Greppmaier Helmut Sachs Tobias Peters Barbara Wilhelm Eberhart Zrenner Dorothea Besch Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants Journal of Ophthalmology |
| title | Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants |
| title_full | Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants |
| title_fullStr | Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants |
| title_full_unstemmed | Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants |
| title_short | Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants |
| title_sort | extraocular surgical approach for placement of subretinal implants in blind patients lessons from cochlear implants |
| url | http://dx.doi.org/10.1155/2015/842518 |
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