Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico
Background: Women living with HIV (WLWH) are at increased risk of persistent HPV infection and HPV-related cancers than persons without HIV. We aimed to describe the utilization of primary and secondary prevention strategies for HPV-related cancers among women by HIV status in Puerto Rico (PR). Meth...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Gynecologic Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352578925000128 |
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| author | Marievelisse Soto-Salgado Melisa Ramos-Sepúlveda Jeslie M. Ramos-Cartagena Maribel Tirado-Gómez Humberto M. Guiot Cristina Muñoz-Masso Lorena González-Sepúlveda Ana Patricia Ortiz |
| author_facet | Marievelisse Soto-Salgado Melisa Ramos-Sepúlveda Jeslie M. Ramos-Cartagena Maribel Tirado-Gómez Humberto M. Guiot Cristina Muñoz-Masso Lorena González-Sepúlveda Ana Patricia Ortiz |
| author_sort | Marievelisse Soto-Salgado |
| collection | DOAJ |
| description | Background: Women living with HIV (WLWH) are at increased risk of persistent HPV infection and HPV-related cancers than persons without HIV. We aimed to describe the utilization of primary and secondary prevention strategies for HPV-related cancers among women by HIV status in Puerto Rico (PR). Methods: We performed a secondary data analysis of women aged 21+ years (n = 469) evaluated at the Anal Neoplasia Clinic (ANC) of the University of Puerto Rico Comprehensive Cancer Center between 2014 and 2023. The outcomes were history of HPV vaccination, anal Pap screening, and cervical Pap screening in the past 3 years. Descriptive statistics were employed to characterize the study population and comparisons were made by HIV status. Results: Women’s mean age in our study was 50.2 ± 12.1 years; 75.7 % were living with HIV. Among women who were age-eligible for HPV vaccination, 21.7 % reported receiving the HPV vaccine; WLWH were less likely vaccinated than women without HIV (14.7 % vs. 38.7 %, p < 0.01). Prevalence of cervical and anal Pap screening were significantly higher among WLWH (98.6 % and 89.9 %, respectively) than in women without HIV (94.4 % and 47.7 %, respectively). Several risk factors for HPV-related disease were more common among WLWH, such as age at first sexual encounter (≤ 16 years) (54.7 %), more than six lifetime sexual partners (43.1 %), and being a current smoker (23.6 %). Conclusions: Although we observed high uptake of cervical and anal Pap screening in this clinic-based sample, HPV vaccination was deficient. Future studies should involve developing tailored cancer prevention strategies for WLWH to increase HPV vaccination uptake. |
| format | Article |
| id | doaj-art-ec1c1a8e58ce4b25a8a2cd7ebd738c4d |
| institution | Kabale University |
| issn | 2352-5789 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gynecologic Oncology Reports |
| spelling | doaj-art-ec1c1a8e58ce4b25a8a2cd7ebd738c4d2025-02-08T05:00:38ZengElsevierGynecologic Oncology Reports2352-57892025-02-0157101687Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto RicoMarievelisse Soto-Salgado0Melisa Ramos-Sepúlveda1Jeslie M. Ramos-Cartagena2Maribel Tirado-Gómez3Humberto M. Guiot4Cristina Muñoz-Masso5Lorena González-Sepúlveda6Ana Patricia Ortiz7University of Puerto Rico (UPR) Comprehensive Cancer Center, Division of Cancer Control and Population Sciences, San Juan, PR, United States; Corresponding author at: University of Puerto Rico Comprehensive Cancer Center, PO Box 363027, San Juan, PR, United States.University of Puerto Rico (UPR) Comprehensive Cancer Center, Division of Cancer Control and Population Sciences, San Juan, PR, United States; UPR Comprehensive Cancer Center, Cancer Prevention and Control Research (CAPAC) Training Program, San Juan, PR, United StatesUniversity of Puerto Rico (UPR) Comprehensive Cancer Center, Division of Cancer Control and Population Sciences, San Juan, PR, United StatesUPR Comprehensive Cancer Center, Division of Clinical and Translational Cancer Research, San Juan, PR, United States; UPR Medical Sciences Campus, School of Medicine, Department of Medicine, San Juan, PR, United StatesUPR Comprehensive Cancer Center, Division of Clinical and Translational Cancer Research, San Juan, PR, United States; UPR Medical Sciences Campus, School of Medicine, Department of Medicine, San Juan, PR, United States; UPR Medical Sciences Campus, School of Medicine, Department of Microbiology and Medical Zoology, San Juan, PR, United StatesUPR Comprehensive Cancer Center, Division of Clinical and Translational Cancer Research, San Juan, PR, United StatesUniversity of Puerto Rico (UPR) Comprehensive Cancer Center, Division of Cancer Control and Population Sciences, San Juan, PR, United StatesUniversity of Puerto Rico (UPR) Comprehensive Cancer Center, Division of Cancer Control and Population Sciences, San Juan, PR, United States; UPR Comprehensive Cancer Center, Cancer Prevention and Control Research (CAPAC) Training Program, San Juan, PR, United States; UPR Medical Sciences Campus, Graduate School of Public Health, Department of Biostatistics and Epidemiology, San Juan, PR, United StatesBackground: Women living with HIV (WLWH) are at increased risk of persistent HPV infection and HPV-related cancers than persons without HIV. We aimed to describe the utilization of primary and secondary prevention strategies for HPV-related cancers among women by HIV status in Puerto Rico (PR). Methods: We performed a secondary data analysis of women aged 21+ years (n = 469) evaluated at the Anal Neoplasia Clinic (ANC) of the University of Puerto Rico Comprehensive Cancer Center between 2014 and 2023. The outcomes were history of HPV vaccination, anal Pap screening, and cervical Pap screening in the past 3 years. Descriptive statistics were employed to characterize the study population and comparisons were made by HIV status. Results: Women’s mean age in our study was 50.2 ± 12.1 years; 75.7 % were living with HIV. Among women who were age-eligible for HPV vaccination, 21.7 % reported receiving the HPV vaccine; WLWH were less likely vaccinated than women without HIV (14.7 % vs. 38.7 %, p < 0.01). Prevalence of cervical and anal Pap screening were significantly higher among WLWH (98.6 % and 89.9 %, respectively) than in women without HIV (94.4 % and 47.7 %, respectively). Several risk factors for HPV-related disease were more common among WLWH, such as age at first sexual encounter (≤ 16 years) (54.7 %), more than six lifetime sexual partners (43.1 %), and being a current smoker (23.6 %). Conclusions: Although we observed high uptake of cervical and anal Pap screening in this clinic-based sample, HPV vaccination was deficient. Future studies should involve developing tailored cancer prevention strategies for WLWH to increase HPV vaccination uptake.http://www.sciencedirect.com/science/article/pii/S2352578925000128HIVCervical Pap screeningAnal Pap screeningHPV vaccineHispanicsPuerto Rico |
| spellingShingle | Marievelisse Soto-Salgado Melisa Ramos-Sepúlveda Jeslie M. Ramos-Cartagena Maribel Tirado-Gómez Humberto M. Guiot Cristina Muñoz-Masso Lorena González-Sepúlveda Ana Patricia Ortiz Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico Gynecologic Oncology Reports HIV Cervical Pap screening Anal Pap screening HPV vaccine Hispanics Puerto Rico |
| title | Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico |
| title_full | Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico |
| title_fullStr | Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico |
| title_full_unstemmed | Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico |
| title_short | Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico |
| title_sort | disparities in the uptake of hpv related cancer prevention strategies among women by hiv status in puerto rico |
| topic | HIV Cervical Pap screening Anal Pap screening HPV vaccine Hispanics Puerto Rico |
| url | http://www.sciencedirect.com/science/article/pii/S2352578925000128 |
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