Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome
Aims. The aim of this study was to investigate the motor control and central silent period (CSP) in restless legs syndrome (RLS). Methods. Transcranial magnetic stimulation was focused on the dominant and nondominant hemispheric areas of motor cortex in six subjects with RLS and six controls. The re...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2012/628949 |
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| author | Aulikki Ahlgrén-Rimpiläinen Hannu Lauerma Seppo Kähkönen Juha Markkula Ilpo Rimpiläinen |
| author_facet | Aulikki Ahlgrén-Rimpiläinen Hannu Lauerma Seppo Kähkönen Juha Markkula Ilpo Rimpiläinen |
| author_sort | Aulikki Ahlgrén-Rimpiläinen |
| collection | DOAJ |
| description | Aims. The aim of this study was to investigate the motor control and central silent period (CSP) in restless legs syndrome (RLS). Methods. Transcranial magnetic stimulation was focused on the dominant and nondominant hemispheric areas of motor cortex in six subjects with RLS and six controls. The responses were recorded on the contralateral abductor digiti minimi (ADM) and tibialis anterior (TA) muscles with intramuscular needle electrodes. Results. No significant differences were found in the motor conduction or central motor conduction time, in the latency, or in the duration of the CSPs between or within the groups, but multiple CSPs were observed in both groups. The number of the CSPs was significantly higher in both ADMs and in the dominant TA (P≤0.01) in the RLS group compared to the controls. Conclusion. Descending motor pathways functioned correctly in both groups. The occurrence of the recurrent CSPs predominantly in the RLS group could be a sign of a change of function in the inhibitory control system. Further research is needed to clarify the role of the intramuscular recording technique and especially the role of the subcortical generators in the feedback regulation of the central nervous system in RLS. |
| format | Article |
| id | doaj-art-ec16ec74f49648a99aac775984bb432c |
| institution | Kabale University |
| issn | 2090-1852 2090-1860 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neurology Research International |
| spelling | doaj-art-ec16ec74f49648a99aac775984bb432c2025-02-03T05:54:09ZengWileyNeurology Research International2090-18522090-18602012-01-01201210.1155/2012/628949628949Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs SyndromeAulikki Ahlgrén-Rimpiläinen0Hannu Lauerma1Seppo Kähkönen2Juha Markkula3Ilpo Rimpiläinen4Forensic Psychiatry, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, FinlandForensic Psychiatry, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, FinlandBioMag Laboratory, Helsinki University Central Hospital (HUCH), P.O. Box 340, 00029, Helsinki, FinlandNeuropsychiatric Outpatient Clinic and the Sleep Research Unit, Turku University Hospital, University of Turku, P.O. Box 52, 20521 Turku, FinlandDepartment of Clinical Neurophysiology, Helsinki University Central Hospital, P.O. Box 1020, 10601 Helsinki, FinlandAims. The aim of this study was to investigate the motor control and central silent period (CSP) in restless legs syndrome (RLS). Methods. Transcranial magnetic stimulation was focused on the dominant and nondominant hemispheric areas of motor cortex in six subjects with RLS and six controls. The responses were recorded on the contralateral abductor digiti minimi (ADM) and tibialis anterior (TA) muscles with intramuscular needle electrodes. Results. No significant differences were found in the motor conduction or central motor conduction time, in the latency, or in the duration of the CSPs between or within the groups, but multiple CSPs were observed in both groups. The number of the CSPs was significantly higher in both ADMs and in the dominant TA (P≤0.01) in the RLS group compared to the controls. Conclusion. Descending motor pathways functioned correctly in both groups. The occurrence of the recurrent CSPs predominantly in the RLS group could be a sign of a change of function in the inhibitory control system. Further research is needed to clarify the role of the intramuscular recording technique and especially the role of the subcortical generators in the feedback regulation of the central nervous system in RLS.http://dx.doi.org/10.1155/2012/628949 |
| spellingShingle | Aulikki Ahlgrén-Rimpiläinen Hannu Lauerma Seppo Kähkönen Juha Markkula Ilpo Rimpiläinen Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome Neurology Research International |
| title | Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome |
| title_full | Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome |
| title_fullStr | Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome |
| title_full_unstemmed | Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome |
| title_short | Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome |
| title_sort | recurrent csps after transcranial magnetic stimulation of motor cortex in restless legs syndrome |
| url | http://dx.doi.org/10.1155/2012/628949 |
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