Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases

Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases

Abstract Alzheimer’s disease (AD) is a multifactorial disease with both genetic and environmental factors contributing to its etiology. Previous evidence has implicated disturbed insulin signaling as a key mechanism that plays a role in both neurodegenerative diseases such as AD and comorbid somatic...

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Main Authors: I. Hyun Ruisch, Joanna Widomska, Ward De Witte, Nina R. Mota, Giuseppe Fanelli, Veerle Van Gils, Willemijn J. Jansen, Stephanie J. B. Vos, Abel Fóthi, Csaba Barta, Simone Berkel, Kazi A. Alam, Aurora Martinez, Jan Haavik, Aet O’Leary, David Slattery, Mairéad Sullivan, Jeffrey Glennon, Jan K. Buitelaar, Janita Bralten, Barbara Franke, Geert Poelmans
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Alzheimer’s Research & Therapy
Online Access:https://doi.org/10.1186/s13195-024-01609-2
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