Research progress in copy number variation in ovarian cancer
Genetic variation is one of the important factors leading to the incidence and development of cancer. Copy number variation is an important source of genetic diversity， which can be expressed as gene amplification or deletion in structure， and is related to the occurrence and development of differen...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of New Medicine
2024-09-01
|
| Series: | Xin yixue |
| Subjects: | |
| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1729126414121-1929580349.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850184869695455232 |
|---|---|
| author | SUN Mengna, XU Ying, REN Chenlu, YAN Yufan, CHEN Zhihao, YANG Hong |
| author_facet | SUN Mengna, XU Ying, REN Chenlu, YAN Yufan, CHEN Zhihao, YANG Hong |
| author_sort | SUN Mengna, XU Ying, REN Chenlu, YAN Yufan, CHEN Zhihao, YANG Hong |
| collection | DOAJ |
| description | Genetic variation is one of the important factors leading to the incidence and development of cancer. Copy number variation is an important source of genetic diversity， which can be expressed as gene amplification or deletion in structure， and is related to the occurrence and development of different tumors. High-throughput sequencing and gene chip technology can be adopted to detect the variation of copy number， and provide relevant information about tumor molecular characteristics， prognosis and treatment， which is conducive to more accurate diagnosis and treatment decisions for patients in clinical practice. Ovarian cancer is one of the female reproductive system diseases with the highest mortality rate. Understanding its pathogenesis is of significance for improving the survival rate of ovarian cancer. At present， the specific role and mechanism of copy number variation in ovarian cancer are still unclear. In this article， relevant copy number variation in ovarian cancer was reviewed based on the existing research results， aiming to provide novel ideas and methods for the prevention， diagnosis and treatment of ovarian cancer. |
| format | Article |
| id | doaj-art-ec141bd422534fbaa01ffa5c643f4513 |
| institution | OA Journals |
| issn | 0253-9802 |
| language | zho |
| publishDate | 2024-09-01 |
| publisher | Editorial Office of Journal of New Medicine |
| record_format | Article |
| series | Xin yixue |
| spelling | doaj-art-ec141bd422534fbaa01ffa5c643f45132025-08-20T02:16:55ZzhoEditorial Office of Journal of New MedicineXin yixue0253-98022024-09-0155973874410.3969/j.issn.0253-9802.2024.09.009Research progress in copy number variation in ovarian cancerSUN Mengna, XU Ying, REN Chenlu, YAN Yufan, CHEN Zhihao, YANG Hong0Department of Gynecology and Obstetrics， the First Affiliated Hospital of Air Force Military Medical University， Xi’ an 710032， ChinaGenetic variation is one of the important factors leading to the incidence and development of cancer. Copy number variation is an important source of genetic diversity， which can be expressed as gene amplification or deletion in structure， and is related to the occurrence and development of different tumors. High-throughput sequencing and gene chip technology can be adopted to detect the variation of copy number， and provide relevant information about tumor molecular characteristics， prognosis and treatment， which is conducive to more accurate diagnosis and treatment decisions for patients in clinical practice. Ovarian cancer is one of the female reproductive system diseases with the highest mortality rate. Understanding its pathogenesis is of significance for improving the survival rate of ovarian cancer. At present， the specific role and mechanism of copy number variation in ovarian cancer are still unclear. In this article， relevant copy number variation in ovarian cancer was reviewed based on the existing research results， aiming to provide novel ideas and methods for the prevention， diagnosis and treatment of ovarian cancer.https://www.xinyixue.cn/fileup/0253-9802/PDF/1729126414121-1929580349.pdfcopy number variation|ovarian cancer|high-throughput sequencing|gene chip|genetic variation |
| spellingShingle | SUN Mengna, XU Ying, REN Chenlu, YAN Yufan, CHEN Zhihao, YANG Hong Research progress in copy number variation in ovarian cancer Xin yixue copy number variation|ovarian cancer|high-throughput sequencing|gene chip|genetic variation |
| title | Research progress in copy number variation in ovarian cancer |
| title_full | Research progress in copy number variation in ovarian cancer |
| title_fullStr | Research progress in copy number variation in ovarian cancer |
| title_full_unstemmed | Research progress in copy number variation in ovarian cancer |
| title_short | Research progress in copy number variation in ovarian cancer |
| title_sort | research progress in copy number variation in ovarian cancer |
| topic | copy number variation|ovarian cancer|high-throughput sequencing|gene chip|genetic variation |
| url | https://www.xinyixue.cn/fileup/0253-9802/PDF/1729126414121-1929580349.pdf |
| work_keys_str_mv | AT sunmengnaxuyingrenchenluyanyufanchenzhihaoyanghong researchprogressincopynumbervariationinovariancancer |