Informationstheoretisches Modell der Carcinogenese

The effects of chemical and physical agents on genetic material have been explained by the interaction of the cell with its immediate environment. Another possibility of cancerogenesis stems from the thermodynamic- and information theory-based premise that cancerogens must all act on the genom of a...

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Main Author: H. Schaltegger
Format: Article
Language:deu
Published: Swiss Chemical Society 1972-06-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9013
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author H. Schaltegger
author_facet H. Schaltegger
author_sort H. Schaltegger
collection DOAJ
description The effects of chemical and physical agents on genetic material have been explained by the interaction of the cell with its immediate environment. Another possibility of cancerogenesis stems from the thermodynamic- and information theory-based premise that cancerogens must all act on the genom of a cell with the same code. In animal organisms the 1010 internal and external receptors and the nerve cells of the central, peripheral and intramural systems are the only means available for the transformation of external stimuli into the organism’s own code (RNA, DNA and proteins). By way of the interaction of the epithelial cells (high rate of cell division) and the nerve cells in the adult organism unable to reproduce) which both originate from the same germ layer, arises after many thousands of cell generations through the “reversible production of code molecules” an “exo-DNA” (phase 1). The combination of these “quasi-virus-DNA” with the DNA of the mother cell (i. e. epithelial cell) would produce a tumor cell which over many generations whould develop into an autonomous, host-specific parastited organism (phase 2).
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spelling doaj-art-ec11b486fb834351aeb1e7d756598e392025-08-20T03:53:27ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241972-06-0126610.2533/chimia.1972.303Informationstheoretisches Modell der CarcinogeneseH. Schaltegger0Institut für organische Chemie der Universität, CH-3000 Bern 9 The effects of chemical and physical agents on genetic material have been explained by the interaction of the cell with its immediate environment. Another possibility of cancerogenesis stems from the thermodynamic- and information theory-based premise that cancerogens must all act on the genom of a cell with the same code. In animal organisms the 1010 internal and external receptors and the nerve cells of the central, peripheral and intramural systems are the only means available for the transformation of external stimuli into the organism’s own code (RNA, DNA and proteins). By way of the interaction of the epithelial cells (high rate of cell division) and the nerve cells in the adult organism unable to reproduce) which both originate from the same germ layer, arises after many thousands of cell generations through the “reversible production of code molecules” an “exo-DNA” (phase 1). The combination of these “quasi-virus-DNA” with the DNA of the mother cell (i. e. epithelial cell) would produce a tumor cell which over many generations whould develop into an autonomous, host-specific parastited organism (phase 2). https://www.chimia.ch/chimia/article/view/9013
spellingShingle H. Schaltegger
Informationstheoretisches Modell der Carcinogenese
CHIMIA
title Informationstheoretisches Modell der Carcinogenese
title_full Informationstheoretisches Modell der Carcinogenese
title_fullStr Informationstheoretisches Modell der Carcinogenese
title_full_unstemmed Informationstheoretisches Modell der Carcinogenese
title_short Informationstheoretisches Modell der Carcinogenese
title_sort informationstheoretisches modell der carcinogenese
url https://www.chimia.ch/chimia/article/view/9013
work_keys_str_mv AT hschaltegger informationstheoretischesmodelldercarcinogenese