Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders
The correct treatment of portal hypertension associated with myeloproliferative disorders remains uncertain. Splenectomy has been advocated by some to eliminate the forward flow component of the portal hypertension and thus reduce portal pressure. The authors describe three recent cases of myeloprol...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
1994-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1994/632862 |
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| _version_ | 1850165244801843200 |
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| author | Samuel S Lee Guido Van Rosendaal Thomas E Lay James K Kelly Graham F Pineo |
| author_facet | Samuel S Lee Guido Van Rosendaal Thomas E Lay James K Kelly Graham F Pineo |
| author_sort | Samuel S Lee |
| collection | DOAJ |
| description | The correct treatment of portal hypertension associated with myeloproliferative disorders remains uncertain. Splenectomy has been advocated by some to eliminate the forward flow component of the portal hypertension and thus reduce portal pressure. The authors describe three recent cases of myeloproliferative disorder in whom splenectomy failed to achieve any significant amelioration of portal hypertension, with in-depth hemodynamic studies in one patient. Based on these experiences, the authors suggest that splenectomy is not the optimum treatment of the portal hypertension
associated with myeloproliferative disorders. |
| format | Article |
| id | doaj-art-ec0a922e44a349459e81723baecbab74 |
| institution | OA Journals |
| issn | 0835-7900 |
| language | English |
| publishDate | 1994-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-ec0a922e44a349459e81723baecbab742025-08-20T02:21:47ZengWileyCanadian Journal of Gastroenterology0835-79001994-01-01829710010.1155/1994/632862Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative DisordersSamuel S Lee0Guido Van Rosendaal1Thomas E Lay2James K Kelly3Graham F Pineo4Departments of Medicine and Pathology, University of Calgary, Calgary, Alberta, CanadaDepartments of Medicine and Pathology, University of Calgary, Calgary, Alberta, CanadaDepartments of Medicine and Pathology, University of Calgary, Calgary, Alberta, CanadaDepartments of Medicine and Pathology, University of Calgary, Calgary, Alberta, CanadaDepartments of Medicine and Pathology, University of Calgary, Calgary, Alberta, CanadaThe correct treatment of portal hypertension associated with myeloproliferative disorders remains uncertain. Splenectomy has been advocated by some to eliminate the forward flow component of the portal hypertension and thus reduce portal pressure. The authors describe three recent cases of myeloproliferative disorder in whom splenectomy failed to achieve any significant amelioration of portal hypertension, with in-depth hemodynamic studies in one patient. Based on these experiences, the authors suggest that splenectomy is not the optimum treatment of the portal hypertension associated with myeloproliferative disorders.http://dx.doi.org/10.1155/1994/632862 |
| spellingShingle | Samuel S Lee Guido Van Rosendaal Thomas E Lay James K Kelly Graham F Pineo Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders Canadian Journal of Gastroenterology |
| title | Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders |
| title_full | Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders |
| title_fullStr | Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders |
| title_full_unstemmed | Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders |
| title_short | Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders |
| title_sort | failure of splenectomy to ameliorate portal hypertension in myeloproliferative disorders |
| url | http://dx.doi.org/10.1155/1994/632862 |
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