Nanofiber‐Coated CF/PEEK Composite: Boosting Osteogenesis for Enhanced Bone Grafting
Abstract This study presents the fabrication of carbon‐fiber‐reinforced polyetheretherketone (CF/PEEK) by 3D printing, which is subsequently coated with elastic nanofibers by electrospinning. CF/PEEK is an FDA‐approved implantable material possessing excellent mechanical properties similar to those...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2025-07-01
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| Series: | Macromolecular Materials and Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/mame.202400286 |
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| Summary: | Abstract This study presents the fabrication of carbon‐fiber‐reinforced polyetheretherketone (CF/PEEK) by 3D printing, which is subsequently coated with elastic nanofibers by electrospinning. CF/PEEK is an FDA‐approved implantable material possessing excellent mechanical properties similar to those of human cortical bone. As such, it is a prime candidate for replacing conventional metallic implants. However, it is limited by its bioinertness and inferior osteogenic properties. In this study, CF/PEEK is engineered to have improved hydrophilic properties and generated micro/nano‐topographical structures on its surface. This is achieved by electrospinning directly onto the 3D‐printed CF/PEEK with fibers incorporating hydroxyapatite particles and gelatin. The results show that the micro‐/nano‐topographical CF/PEEK demonstrates a significant increase in mineralizing potential compared to non‐coated implants, where no mineralized matrix is observed. These fiber coating modifications to CF/PEEK are a promising and important step forward in the improvement of in vivo implant‐bone osteointegration. |
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| ISSN: | 1438-7492 1439-2054 |