Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case)
Given the high prevalence of allergic and cardiovascular diseases, clinicians must remain vigilant to the possibility of Kounis syndrome (KS), which involves the cooccurrence of an allergic reaction and acute myocardial infarction (AMI). The article describes a case of KS in a 62-year-old patient, w...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2025-06-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/3164 |
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| author | E. V. Kozhevnikova K. G. Pereverzeva A. A. Gurbanova S. S. Yakushin |
| author_facet | E. V. Kozhevnikova K. G. Pereverzeva A. A. Gurbanova S. S. Yakushin |
| author_sort | E. V. Kozhevnikova |
| collection | DOAJ |
| description | Given the high prevalence of allergic and cardiovascular diseases, clinicians must remain vigilant to the possibility of Kounis syndrome (KS), which involves the cooccurrence of an allergic reaction and acute myocardial infarction (AMI). The article describes a case of KS in a 62-year-old patient, without atherosclerotic coronary artery disease, during the infusion of a plasma-substitute, dextran, used by the patient for self-medication and resulting anaphylactic shock. The diagnosis of AMI was confirmed by elevated myocardial necrosis biomarkers, as well as electrocardiographic and echocardiographic changes. Patient management adhered to current clinical guidelines for AMI and allergic reactions. The distinctive feature of this clinical case is the development of type I KS triggered by dextran, and the multifactorial etiology of AMI. This case demonstrates the importance of recognising KS, advocates for restricting self-treatment practices, and highlights the need for preventive counselling regarding its potential consequences. |
| format | Article |
| id | doaj-art-ec03b9cffc8b4039afa78da8a93ab762 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-ec03b9cffc8b4039afa78da8a93ab7622025-08-23T10:00:37ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532025-06-0121218218710.20996/1819-6446-2025-31642273Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case)E. V. Kozhevnikova0K. G. Pereverzeva1A. A. Gurbanova2S. S. Yakushin3I. P. Pavlov Ryazan State Medical UniversityI. P. Pavlov Ryazan State Medical UniversityI. P. Pavlov Ryazan State Medical UniversityI. P. Pavlov Ryazan State Medical UniversityGiven the high prevalence of allergic and cardiovascular diseases, clinicians must remain vigilant to the possibility of Kounis syndrome (KS), which involves the cooccurrence of an allergic reaction and acute myocardial infarction (AMI). The article describes a case of KS in a 62-year-old patient, without atherosclerotic coronary artery disease, during the infusion of a plasma-substitute, dextran, used by the patient for self-medication and resulting anaphylactic shock. The diagnosis of AMI was confirmed by elevated myocardial necrosis biomarkers, as well as electrocardiographic and echocardiographic changes. Patient management adhered to current clinical guidelines for AMI and allergic reactions. The distinctive feature of this clinical case is the development of type I KS triggered by dextran, and the multifactorial etiology of AMI. This case demonstrates the importance of recognising KS, advocates for restricting self-treatment practices, and highlights the need for preventive counselling regarding its potential consequences.https://www.rpcardio.online/jour/article/view/3164allergic myocardial infarctionkounis syndromeacute myocardial infarctionanaphylactic shockvasospasmdrug allergydextranself-medication |
| spellingShingle | E. V. Kozhevnikova K. G. Pereverzeva A. A. Gurbanova S. S. Yakushin Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case) Рациональная фармакотерапия в кардиологии allergic myocardial infarction kounis syndrome acute myocardial infarction anaphylactic shock vasospasm drug allergy dextran self-medication |
| title | Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case) |
| title_full | Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case) |
| title_fullStr | Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case) |
| title_full_unstemmed | Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case) |
| title_short | Type I Kounis syndrome developing following administration of a plasma substitute (a clinical case) |
| title_sort | type i kounis syndrome developing following administration of a plasma substitute a clinical case |
| topic | allergic myocardial infarction kounis syndrome acute myocardial infarction anaphylactic shock vasospasm drug allergy dextran self-medication |
| url | https://www.rpcardio.online/jour/article/view/3164 |
| work_keys_str_mv | AT evkozhevnikova typeikounissyndromedevelopingfollowingadministrationofaplasmasubstituteaclinicalcase AT kgpereverzeva typeikounissyndromedevelopingfollowingadministrationofaplasmasubstituteaclinicalcase AT aagurbanova typeikounissyndromedevelopingfollowingadministrationofaplasmasubstituteaclinicalcase AT ssyakushin typeikounissyndromedevelopingfollowingadministrationofaplasmasubstituteaclinicalcase |