Systemic isotretinoin in the management of acne – a patient questionnaire survey

Background: The primary aim was to investigate the appropriateness (as outlined in the South African Acne Treatment Guideline 1) for the prescription of systemic isotretinoin in the management and counselling of acne in the Nelson Mandela Bay Metropole. Methods: A questionnaire was distributed to...

Full description

Saved in:
Bibliographic Details
Main Authors: Solé Burger, Ilse Truter, Suzette M. Blignault, Danie J.L. Venter
Format: Article
Language:English
Published: AOSIS 2009-10-01
Series:South African Family Practice
Subjects:
Online Access:https://safpj.co.za/index.php/safpj/article/view/1310
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849234055795572736
author Solé Burger
Ilse Truter
Suzette M. Blignault
Danie J.L. Venter
author_facet Solé Burger
Ilse Truter
Suzette M. Blignault
Danie J.L. Venter
author_sort Solé Burger
collection DOAJ
description Background: The primary aim was to investigate the appropriateness (as outlined in the South African Acne Treatment Guideline 1) for the prescription of systemic isotretinoin in the management and counselling of acne in the Nelson Mandela Bay Metropole. Methods: A questionnaire was distributed to patients receiving systemic isotretinoin by 30 community pharmacies. The response rate was 29.2% (57 respondents). Results: The acne medication history revealed that commercial brands of beauty products were used by 57.9% of respondents, topical benzoyl peroxide by 22.8%, and systemic cotrimoxazole by 19.3%. Only nine females used an oral contraceptive as acne treatment prior to isotretinoin. The average daily dose of isotretinoin was 44.2 (SD=16.9) mg. Half of the respondents received a suboptimal cumulative dosage of isotretinoin. The average prescribed duration of isotretinoin therapy was 6.2 months. Adequate counselling was received by only 57.9% of patients. A third of the patients who were able to fall pregnant received recommendations for contraception. Pregnancy tests were conducted in only two females. Just over 40% of patients reported a complete clearance of acne lesions. Conclusions: Many prescribers did not follow the recommendations for isotretinoin prescription. The counselling of patients regarding isotretinoin therapy was substandard, especially with respect to pregnancy prevention.
format Article
id doaj-art-ec036470c8534b6487e0cfecff647c7f
institution Kabale University
issn 2078-6190
2078-6204
language English
publishDate 2009-10-01
publisher AOSIS
record_format Article
series South African Family Practice
spelling doaj-art-ec036470c8534b6487e0cfecff647c7f2025-08-20T04:03:17ZengAOSISSouth African Family Practice2078-61902078-62042009-10-0151510.1080/20786204.2009.108738971093Systemic isotretinoin in the management of acne – a patient questionnaire surveySolé Burger0Ilse Truter1Suzette M. Blignault2Danie J.L. Venter3Drug Utilization Research Unit, Department of Pharmacy, Nelson Mandela Metropolitan UniversityDrug Utilization Research Unit, Department of Pharmacy, Nelson Mandela Metropolitan UniversityDrug Utilization Research Unit, Department of Pharmacy, Nelson Mandela Metropolitan UniversityDepartment of Statistics, Nelson Mandela Metropolitan UniversityBackground: The primary aim was to investigate the appropriateness (as outlined in the South African Acne Treatment Guideline 1) for the prescription of systemic isotretinoin in the management and counselling of acne in the Nelson Mandela Bay Metropole. Methods: A questionnaire was distributed to patients receiving systemic isotretinoin by 30 community pharmacies. The response rate was 29.2% (57 respondents). Results: The acne medication history revealed that commercial brands of beauty products were used by 57.9% of respondents, topical benzoyl peroxide by 22.8%, and systemic cotrimoxazole by 19.3%. Only nine females used an oral contraceptive as acne treatment prior to isotretinoin. The average daily dose of isotretinoin was 44.2 (SD=16.9) mg. Half of the respondents received a suboptimal cumulative dosage of isotretinoin. The average prescribed duration of isotretinoin therapy was 6.2 months. Adequate counselling was received by only 57.9% of patients. A third of the patients who were able to fall pregnant received recommendations for contraception. Pregnancy tests were conducted in only two females. Just over 40% of patients reported a complete clearance of acne lesions. Conclusions: Many prescribers did not follow the recommendations for isotretinoin prescription. The counselling of patients regarding isotretinoin therapy was substandard, especially with respect to pregnancy prevention.https://safpj.co.za/index.php/safpj/article/view/1310acneisotretinoinskin conditionsdrug utilisationquestionnaire surveydermatology
spellingShingle Solé Burger
Ilse Truter
Suzette M. Blignault
Danie J.L. Venter
Systemic isotretinoin in the management of acne – a patient questionnaire survey
South African Family Practice
acne
isotretinoin
skin conditions
drug utilisation
questionnaire survey
dermatology
title Systemic isotretinoin in the management of acne – a patient questionnaire survey
title_full Systemic isotretinoin in the management of acne – a patient questionnaire survey
title_fullStr Systemic isotretinoin in the management of acne – a patient questionnaire survey
title_full_unstemmed Systemic isotretinoin in the management of acne – a patient questionnaire survey
title_short Systemic isotretinoin in the management of acne – a patient questionnaire survey
title_sort systemic isotretinoin in the management of acne a patient questionnaire survey
topic acne
isotretinoin
skin conditions
drug utilisation
questionnaire survey
dermatology
url https://safpj.co.za/index.php/safpj/article/view/1310
work_keys_str_mv AT soleburger systemicisotretinoininthemanagementofacneapatientquestionnairesurvey
AT ilsetruter systemicisotretinoininthemanagementofacneapatientquestionnairesurvey
AT suzettemblignault systemicisotretinoininthemanagementofacneapatientquestionnairesurvey
AT daniejlventer systemicisotretinoininthemanagementofacneapatientquestionnairesurvey