The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies

Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic. Serologic HLA matching has been the standard for solid o...

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Bibliographic Details
Main Authors: Edward J. Filippone, John L. Farber
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/5197396
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