The Potential Therapeutic Effects of Tadalafil on the Endothelium in a Subarachnoid Hemorrhage Animal Model: Insights from Immunohistochemical Staining

The Potential Therapeutic Effects of Tadalafil on the Endothelium in a Subarachnoid Hemorrhage Animal Model: Insights from Immunohistochemical Staining

This study investigated the potential of phosphodiesterase type 5 (PDE-5) inhibitors, specifically tadalafil, in preventing the delayed cerebral ischemia (DCI) post-rupture of cerebral aneurysms. A total of 19 rabbits were used in this study, divided into different treatment groups, including nimodi...

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Bibliographic Details
Main Authors: Kwang Hyon Park, Hyon-Jo Kwon, Eun-Oh Jeong, Hyeon-Song Koh, Jeongwook Lim
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Current Issues in Molecular Biology
Subjects:
aneurysm
subarachnoid hemorrhage
delayed cerebral ischemia
nimodipine
tadalafil
endothelium
Online Access:https://www.mdpi.com/1467-3045/46/9/567
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