Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017

Introduction: Polypharmacy, defined as the simultaneous consumption of 3 or more medications, is a significant concern in older adults, particularly in communities with limited access to healthcare services and adverse living conditions. This study focuses on vulnerable populations in high-Andean c...

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Main Authors: Marquina-Torres, Pierina E, Marquez-Yataco, Juan E., Ñaña-Cordova, Alvaro Micael, Jordan-Beisaga, Itala, Parodi, José F., Apolaya, Moisés, Runzer-Colmenares, Fernando M.
Format: Article
Language:Spanish
Published: Universidad de Antioquia 2025-01-01
Series:Iatreia
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Online Access:https://revistas.udea.edu.co/index.php/iatreia/article/view/354663
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author Marquina-Torres, Pierina E,
Marquez-Yataco, Juan E.
Ñaña-Cordova, Alvaro Micael
Jordan-Beisaga, Itala
Parodi, José F.
Apolaya, Moisés
Runzer-Colmenares, Fernando M.
author_facet Marquina-Torres, Pierina E,
Marquez-Yataco, Juan E.
Ñaña-Cordova, Alvaro Micael
Jordan-Beisaga, Itala
Parodi, José F.
Apolaya, Moisés
Runzer-Colmenares, Fernando M.
author_sort Marquina-Torres, Pierina E,
collection DOAJ
description Introduction: Polypharmacy, defined as the simultaneous consumption of 3 or more medications, is a significant concern in older adults, particularly in communities with limited access to healthcare services and adverse living conditions. This study focuses on vulnerable populations in high-Andean communities of Peru. Objectives: To determine the factors associated with polypharmacy in older adults from 12 high-Andean communities in Peru. Methods: This observational, descriptive, and cross-sectional study included a sample of 399 elderly individuals selected through census sampling with a minimum response rate of 95%. The "Frailty in Older Adults from the Peruvian Andes" questionnaire was utilized. Multivariate analysis was conducted using Chi-square test, Student's t-test, Mann-Whitney U test, and regression analysis for independent groups. Results: Of the participants, 58.7% (n=234) were women, and 32.8% exhibited polypharmacy. The variables most strongly associated with polypharmacy were retirement (CI 2.07 - 8.13), previous hospitalizations (CI 0.09 - 0.31), alcohol consumption (CI 2.04 - 6.28), tobacco use (CI 2.78 - 10.12), and hypertension (CI 1.14 - 4.68). Conclusions: Polypharmacy in older adults is influenced by sociocultural and demographic factors such as retirement, alcohol and tobacco consumption, and hypertension. Altitude did not show a significant association with polypharmacy.
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spelling doaj-art-ebfbc73d847743aba17340e250bc303f2025-01-17T13:24:55ZspaUniversidad de AntioquiaIatreia0121-07932011-79652025-01-01381324310.17533/udea.iatreia.305Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017Marquina-Torres, Pierina E,0https://orcid.org/0000-0001-8878-6324Marquez-Yataco, Juan E. 1https://orcid.org/0009-0009-0412-9024Ñaña-Cordova, Alvaro Micael2https://orcid.org/0000-0002-1556-0954Jordan-Beisaga, Itala 3https://orcid.org/0000-0003-4942-6400Parodi, José F. 4https://orcid.org/0000-0002-0336-0584Apolaya, Moisés5https://orcid.org/0000-0001-5650-9998Runzer-Colmenares, Fernando M.6https://orcid.org/0000-0003-4045-0260Universidad de San Martín de Porres, Lima, PerúUniversidad de San Martín de Porres, Lima, PerúUniversidad Científica del Sur, Lima, PerúUniversidad Científica del Sur, Lima, PerúSan Martín de Porres, Lima, PerúUniversidad de San Martín de Porres, Lima, PerúUniversidad Científica del Sur, Lima, PerúIntroduction: Polypharmacy, defined as the simultaneous consumption of 3 or more medications, is a significant concern in older adults, particularly in communities with limited access to healthcare services and adverse living conditions. This study focuses on vulnerable populations in high-Andean communities of Peru. Objectives: To determine the factors associated with polypharmacy in older adults from 12 high-Andean communities in Peru. Methods: This observational, descriptive, and cross-sectional study included a sample of 399 elderly individuals selected through census sampling with a minimum response rate of 95%. The "Frailty in Older Adults from the Peruvian Andes" questionnaire was utilized. Multivariate analysis was conducted using Chi-square test, Student's t-test, Mann-Whitney U test, and regression analysis for independent groups. Results: Of the participants, 58.7% (n=234) were women, and 32.8% exhibited polypharmacy. The variables most strongly associated with polypharmacy were retirement (CI 2.07 - 8.13), previous hospitalizations (CI 0.09 - 0.31), alcohol consumption (CI 2.04 - 6.28), tobacco use (CI 2.78 - 10.12), and hypertension (CI 1.14 - 4.68). Conclusions: Polypharmacy in older adults is influenced by sociocultural and demographic factors such as retirement, alcohol and tobacco consumption, and hypertension. Altitude did not show a significant association with polypharmacy.https://revistas.udea.edu.co/index.php/iatreia/article/view/354663agedpolypharmacyrisk factors
spellingShingle Marquina-Torres, Pierina E,
Marquez-Yataco, Juan E.
Ñaña-Cordova, Alvaro Micael
Jordan-Beisaga, Itala
Parodi, José F.
Apolaya, Moisés
Runzer-Colmenares, Fernando M.
Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017
Iatreia
aged
polypharmacy
risk factors
title Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017
title_full Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017
title_fullStr Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017
title_full_unstemmed Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017
title_short Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017
title_sort factors associated with polypharmacy in older adults from 12 high andean communities in peru 2013 2017
topic aged
polypharmacy
risk factors
url https://revistas.udea.edu.co/index.php/iatreia/article/view/354663
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