Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis

Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis

BackgroundVon Willebrand Factor (VWF) and Neutrophil Extracellular Traps (NETs) are involved in the inflammatory response during thrombi formation and are widely found in thrombi of Acute Ischemic Stroke (AIS) patients. Inflammation may mediate the relationship between cerebrovascular risk factors (...

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Main Authors: Lin Shi, Chunxiao Wei, Guowei Ye, Panpan Zhao, Shiqiang Ma, Yiming Qi, Ruolin Zhou, Yaru Zhang, Yan Zhang, Lingjie Meng, Weihang Xu, Chao Li, Shouchun Wang, Li Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Neurology
Subjects:
stroke
overall leukocyte levels
Von Willebrand factor (VWF)
Neutrophil Extracellular Traps (NETs)
Partial Least Squares Structural Equation Modeling (PLS-SEM)
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1515596/full
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https://www.frontiersin.org/articles/10.3389/fneur.2025.1515596/full

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