METHOD OF DETERMINATION OF 5-METHYL-6-NITRO-7-OXO-1,2,4-TRIAZOLO[1,5-<i>a</i>]PIRIMIDINIDE <i>l-</i>ARGININY - THE ACTIVE COMPONENT OF DRUG «TRIAZID» BY HPLC METHOD

METHOD OF DETERMINATION OF 5-METHYL-6-NITRO-7-OXO-1,2,4-TRIAZOLO[1,5-<i>a</i>]PIRIMIDINIDE <i>l-</i>ARGININY - THE ACTIVE COMPONENT OF DRUG «TRIAZID» BY HPLC METHOD

A procedure for quantitative determination of 5-methyl-6-nitro-7-oxo-1,2,4-triazolo[1,5-a]pirimidinide l -argininy was developed using the HPLC method with UV detection. To achieve the best chromatographic characteristics, it is proposed to use a column with a grafted octadecylsilyl phase 5-100-c18...

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Bibliographic Details
Main Authors: A. V. Baklykov, A. A. Tumashov, S. K. Kotovskaya, E. N. Ulomsky, G. L. Rusinov, V. L. Rusinov, G. A. Artem’ev, D. S. Kopchuk, V. N. Charushin
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
5-methyl-6-nitro-7-oxo-1,2,4-triazolo[1,5-a]pirimidinide l-argininy
triazide
hplc
validation
Online Access:https://www.pharmjournal.ru/jour/article/view/581
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