Antondine Injection-Associated Fixed Drug Eruption: A Case Report
Background: Fixed drug eruption (FDE) is a drug hypersensitivity reaction caused by antibiotics and non-steroidal anti-inflammatory drugs primarily. Antondine injection is a drug used to reduce fever, mainly composed of aminopyrine, antipyrine and barbiturate, and its adverse reactions include anaph...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-01-01
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| Series: | Clinical Medicine Insights: Case Reports |
| Online Access: | https://doi.org/10.1177/11795476251315616 |
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| author | Yan Yang Peng-Fei Li Qiang Ma Xiao-Na Wang Qing Chen Ling-Yun Ma Hao Tang Zhen Wang |
| author_facet | Yan Yang Peng-Fei Li Qiang Ma Xiao-Na Wang Qing Chen Ling-Yun Ma Hao Tang Zhen Wang |
| author_sort | Yan Yang |
| collection | DOAJ |
| description | Background: Fixed drug eruption (FDE) is a drug hypersensitivity reaction caused by antibiotics and non-steroidal anti-inflammatory drugs primarily. Antondine injection is a drug used to reduce fever, mainly composed of aminopyrine, antipyrine and barbiturate, and its adverse reactions include anaphylactic shock, epidermolysis, rash, agranulocytosis, etc. FDE caused by Antondine injection is an uncommon phenomenon, and the drug eruption caused by these ingredients has been reported in the current case report. However, the fatal severe fixed drug eruption caused by it has not been reported. Here, we report a case of severe PDE after treatment with Antondine, highlighting it’s necessary to avoid these medications with this ingredient when using antipyretic medications. |
| format | Article |
| id | doaj-art-ebeb8ae72fbf4a31a657be80af5166fa |
| institution | Kabale University |
| issn | 1179-5476 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Case Reports |
| spelling | doaj-art-ebeb8ae72fbf4a31a657be80af5166fa2025-01-30T15:03:20ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762025-01-011810.1177/11795476251315616Antondine Injection-Associated Fixed Drug Eruption: A Case ReportYan Yang0Peng-Fei Li1Qiang Ma2Xiao-Na Wang3Qing Chen4Ling-Yun Ma5Hao Tang6Zhen Wang7Department of Intensive Care Medicine, Army Medical Center of PLA, Chongqing, ChinaDepartment of Intensive Care Medicine, Army Medical Center of PLA, Chongqing, ChinaDepartment of Pathology, Army Medical Center of PLA, Chongqing, ChinaDepartment of Intensive Care Medicine, Army Medical Center of PLA, Chongqing, ChinaDepartment of Intensive Care Medicine, Army Medical Center of PLA, Chongqing, ChinaDepartment of Intensive Care Medicine, Army Medical Center of PLA, Chongqing, ChinaDepartment of Intensive Care Medicine, Army Medical Center of PLA, Chongqing, ChinaDepartment of Intensive Care Medicine, Army Medical Center of PLA, Chongqing, ChinaBackground: Fixed drug eruption (FDE) is a drug hypersensitivity reaction caused by antibiotics and non-steroidal anti-inflammatory drugs primarily. Antondine injection is a drug used to reduce fever, mainly composed of aminopyrine, antipyrine and barbiturate, and its adverse reactions include anaphylactic shock, epidermolysis, rash, agranulocytosis, etc. FDE caused by Antondine injection is an uncommon phenomenon, and the drug eruption caused by these ingredients has been reported in the current case report. However, the fatal severe fixed drug eruption caused by it has not been reported. Here, we report a case of severe PDE after treatment with Antondine, highlighting it’s necessary to avoid these medications with this ingredient when using antipyretic medications.https://doi.org/10.1177/11795476251315616 |
| spellingShingle | Yan Yang Peng-Fei Li Qiang Ma Xiao-Na Wang Qing Chen Ling-Yun Ma Hao Tang Zhen Wang Antondine Injection-Associated Fixed Drug Eruption: A Case Report Clinical Medicine Insights: Case Reports |
| title | Antondine Injection-Associated Fixed Drug Eruption: A Case Report |
| title_full | Antondine Injection-Associated Fixed Drug Eruption: A Case Report |
| title_fullStr | Antondine Injection-Associated Fixed Drug Eruption: A Case Report |
| title_full_unstemmed | Antondine Injection-Associated Fixed Drug Eruption: A Case Report |
| title_short | Antondine Injection-Associated Fixed Drug Eruption: A Case Report |
| title_sort | antondine injection associated fixed drug eruption a case report |
| url | https://doi.org/10.1177/11795476251315616 |
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