Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review
Abstract Inflammatory myofibroblastic tumor (IMT) is an intermediate malignancy with myofibroblast proliferation and inflammatory cell infiltration with malignant potential. Primary IMTs are predominantly reported in the lungs, while gastric IMTs are very rare. Therefore, no guidelines exist for the...
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| Language: | English |
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2024-04-01
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| Online Access: | https://doi.org/10.1002/deo2.243 |
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| author | Yuka Masuda Yoshikazu Kanazawa Osamu Goto Daisuke Kakinuma Kazutoshi Higuchi Eriko Koizumi Ryosuke Nakata Nobuyuki Sakurazawa Fumihiko Ando Mikito Suzuki Toshiro Yoshiyuki Shunji Kato Ryuji Ohashi Mitsuru Kaise Katsuhiko Iwakiri Hiroshi Yoshida |
| author_facet | Yuka Masuda Yoshikazu Kanazawa Osamu Goto Daisuke Kakinuma Kazutoshi Higuchi Eriko Koizumi Ryosuke Nakata Nobuyuki Sakurazawa Fumihiko Ando Mikito Suzuki Toshiro Yoshiyuki Shunji Kato Ryuji Ohashi Mitsuru Kaise Katsuhiko Iwakiri Hiroshi Yoshida |
| author_sort | Yuka Masuda |
| collection | DOAJ |
| description | Abstract Inflammatory myofibroblastic tumor (IMT) is an intermediate malignancy with myofibroblast proliferation and inflammatory cell infiltration with malignant potential. Primary IMTs are predominantly reported in the lungs, while gastric IMTs are very rare. Therefore, no guidelines exist for the diagnosis and treatment of gastric IMTs. The present case is a 39‐year‐old man diagnosed with an asymptomatic gastric submucosal tumor. Considering the malignancy of the tumor, we selected non‐exposed endoscopic wall‐inversion surgery as the resection method and successfully performed local resection. Histopathological analysis showed myofibroblast proliferation and inflammatory cell infiltration, with a diagnosis of primary gastric IMT and negative resection margins. Immunohistochemical staining was negative for anaplastic lymphoma kinase. To the best of our knowledge, including our case, there have been 52 reported cases of primary gastric IMTs that have been treated, with several recurrent cases. In this study, we report the first case of local resection of gastric IMT using non‐exposed endoscopic wall‐inversion surgery, with a literature review. |
| format | Article |
| id | doaj-art-ebea6da62ae14d5dae28b8572ebbf928 |
| institution | Kabale University |
| issn | 2692-4609 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-ebea6da62ae14d5dae28b8572ebbf9282025-08-20T03:59:36ZengWileyDEN Open2692-46092024-04-0141n/an/a10.1002/deo2.243Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature reviewYuka Masuda0Yoshikazu Kanazawa1Osamu Goto2Daisuke Kakinuma3Kazutoshi Higuchi4Eriko Koizumi5Ryosuke Nakata6Nobuyuki Sakurazawa7Fumihiko Ando8Mikito Suzuki9Toshiro Yoshiyuki10Shunji Kato11Ryuji Ohashi12Mitsuru Kaise13Katsuhiko Iwakiri14Hiroshi Yoshida15Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastroenterology Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastroenterology Nippon Medical School Hospital Tokyo JapanDepartment of Gastroenterology Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanDepartment of Diagnostic Pathology Nippon Medical School Hospital Tokyo JapanDepartment of Gastroenterology Nippon Medical School Hospital Tokyo JapanDepartment of Gastroenterology Nippon Medical School Hospital Tokyo JapanDepartment of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo JapanAbstract Inflammatory myofibroblastic tumor (IMT) is an intermediate malignancy with myofibroblast proliferation and inflammatory cell infiltration with malignant potential. Primary IMTs are predominantly reported in the lungs, while gastric IMTs are very rare. Therefore, no guidelines exist for the diagnosis and treatment of gastric IMTs. The present case is a 39‐year‐old man diagnosed with an asymptomatic gastric submucosal tumor. Considering the malignancy of the tumor, we selected non‐exposed endoscopic wall‐inversion surgery as the resection method and successfully performed local resection. Histopathological analysis showed myofibroblast proliferation and inflammatory cell infiltration, with a diagnosis of primary gastric IMT and negative resection margins. Immunohistochemical staining was negative for anaplastic lymphoma kinase. To the best of our knowledge, including our case, there have been 52 reported cases of primary gastric IMTs that have been treated, with several recurrent cases. In this study, we report the first case of local resection of gastric IMT using non‐exposed endoscopic wall‐inversion surgery, with a literature review.https://doi.org/10.1002/deo2.243gastric tumorinflammatory myofibroblastic tumorLECSNEWSstomach |
| spellingShingle | Yuka Masuda Yoshikazu Kanazawa Osamu Goto Daisuke Kakinuma Kazutoshi Higuchi Eriko Koizumi Ryosuke Nakata Nobuyuki Sakurazawa Fumihiko Ando Mikito Suzuki Toshiro Yoshiyuki Shunji Kato Ryuji Ohashi Mitsuru Kaise Katsuhiko Iwakiri Hiroshi Yoshida Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review DEN Open gastric tumor inflammatory myofibroblastic tumor LECS NEWS stomach |
| title | Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review |
| title_full | Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review |
| title_fullStr | Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review |
| title_full_unstemmed | Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review |
| title_short | Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review |
| title_sort | primary gastric inflammatory myofibroblastic tumor treated with non exposed endoscopic wall inversion surgery news a case report and literature review |
| topic | gastric tumor inflammatory myofibroblastic tumor LECS NEWS stomach |
| url | https://doi.org/10.1002/deo2.243 |
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