Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus
Background: Corticosteroids are the most common treatment for oral lichen planus, a long-term immune-related condition, which is considered the most effective treatment. Photobiomodulation is a viable alternative treatment that can successfully treat various pathological disorders by relieving pain...
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| Format: | Article |
| Language: | English |
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College of Dentistry/ University of Baghdad
2025-03-01
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| Series: | Journal of Baghdad College of Dentistry |
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| Online Access: | https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3914 |
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| author | Omar H Soliman Eisa M Hegazy Eman M Abdulhady Asem M Kamel Mahmoud A Attia Nicola Baldini Hayder R Abdulbaqi Ahmed M Fekry Rahma G Mostafa Ahmed M Hussein |
| author_facet | Omar H Soliman Eisa M Hegazy Eman M Abdulhady Asem M Kamel Mahmoud A Attia Nicola Baldini Hayder R Abdulbaqi Ahmed M Fekry Rahma G Mostafa Ahmed M Hussein |
| author_sort | Omar H Soliman |
| collection | DOAJ |
| description |
Background: Corticosteroids are the most common treatment for oral lichen planus, a long-term immune-related condition, which is considered the most effective treatment. Photobiomodulation is a viable alternative treatment that can successfully treat various pathological disorders by relieving pain, decreasing inflammation, and facilitating tissue healing. Unlike steroid medications, photobiomodulation does not have any associated disadvantages. This study aimed to assess and compare the effects of topical application of 0.1% triamcinolone acetonide and photobiomodulation on erosive oral lichen planus. Methods: A randomized controlled clinical trial was conducted in this investigation, which involved 20 patients who were suffering from erosive oral lichen planus. The control group (n= 10) was administered a 0.1% topical solution of triamcinolone acetonide 3 times daily and a miconazole oral gel once daily, for 4 weeks. The patients in the second group (n = 10) engaged in laser therapy twice a week for 8 sessions over 4 weeks, utilizing a 980 nm diode laser with an output power of 300 mw. Pain and clinical scores of patients were evaluated at the start and 4 weeks postoperatively. Results: Both groups were not significantly different from one another, and both had substantial improvements in pain and clinical scores. Conclusions: Low-Level Laser therapy showed potential as a therapeutic approach for treating erosive oral lichen planus, offering an alternative to steroid therapy without the associated adverse effects.
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| format | Article |
| id | doaj-art-ebea62f9631b44a1a88f64b1f23c371f |
| institution | DOAJ |
| issn | 1817-1869 2311-5270 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | College of Dentistry/ University of Baghdad |
| record_format | Article |
| series | Journal of Baghdad College of Dentistry |
| spelling | doaj-art-ebea62f9631b44a1a88f64b1f23c371f2025-08-20T03:19:20ZengCollege of Dentistry/ University of BaghdadJournal of Baghdad College of Dentistry1817-18692311-52702025-03-0137110.26477/jbcd.v37i1.3914Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus Omar H Soliman 0https://orcid.org/0000-0002-0122-4490Eisa M Hegazy1https://orcid.org/0000-0001-8638-0427Eman M Abdulhady2https://orcid.org/0000-0002-3872-1028Asem M Kamel3https://orcid.org/0000-0003-0136-8520Mahmoud A Attia4https://orcid.org/0009-0000-1629-6860Nicola Baldini5https://orcid.org/0000-0001-8182-7090Hayder R Abdulbaqi6https://orcid.org/0000-0002-0606-2830Ahmed M Fekry7https://orcid.org/0000-0003-4224-9210Rahma G Mostafa8https://orcid.org/0009-0006-3568-8767Ahmed M Hussein9https://orcid.org/0000-0002-3367-4402Department of Oral Medicine, Periodontology, and Oral Diagnosis, Faculty of Dentistry, South Valley University, EgyptDermatology, Venerology, and Andrology Department, Faculty of Medicine, South Valley University, EgyptOral Medicine, Periodontology and Oral Diagnosis Department, Faculty of Dentistry, Horus University, EgyptOral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Dental Medicine Faculty, Al-Azhar University (Assiut Branch), Assiut, EgyptOral Pathology Department, Faculty of Dentistry, Al-Azhar University (Assiut Branch), Assiut, Egypt and Faculty of Applied Medical Science, Al-Baha University, Saudi ArabiaOral Surgery and Implantology Department, Hospital Le Scotte Siena, University of Siena, ItalyPeriodontics Department, Collage of Dentistry, University of Baghdad, IraqOral Medicine and Periodontology Department, Faculty of Dentistry, Assiut University, EgyptOral and Maxillofacial Pathology Department, Faculty of Dentistry, Assiut University, EgyptOral and Maxillofacial Pathology Department, Faculty of Dentistry, Assiut University, Egypt Background: Corticosteroids are the most common treatment for oral lichen planus, a long-term immune-related condition, which is considered the most effective treatment. Photobiomodulation is a viable alternative treatment that can successfully treat various pathological disorders by relieving pain, decreasing inflammation, and facilitating tissue healing. Unlike steroid medications, photobiomodulation does not have any associated disadvantages. This study aimed to assess and compare the effects of topical application of 0.1% triamcinolone acetonide and photobiomodulation on erosive oral lichen planus. Methods: A randomized controlled clinical trial was conducted in this investigation, which involved 20 patients who were suffering from erosive oral lichen planus. The control group (n= 10) was administered a 0.1% topical solution of triamcinolone acetonide 3 times daily and a miconazole oral gel once daily, for 4 weeks. The patients in the second group (n = 10) engaged in laser therapy twice a week for 8 sessions over 4 weeks, utilizing a 980 nm diode laser with an output power of 300 mw. Pain and clinical scores of patients were evaluated at the start and 4 weeks postoperatively. Results: Both groups were not significantly different from one another, and both had substantial improvements in pain and clinical scores. Conclusions: Low-Level Laser therapy showed potential as a therapeutic approach for treating erosive oral lichen planus, offering an alternative to steroid therapy without the associated adverse effects. https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3914PhotobiomodulationOral Lichen PlanusTopical SteroidDiode Laser |
| spellingShingle | Omar H Soliman Eisa M Hegazy Eman M Abdulhady Asem M Kamel Mahmoud A Attia Nicola Baldini Hayder R Abdulbaqi Ahmed M Fekry Rahma G Mostafa Ahmed M Hussein Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus Journal of Baghdad College of Dentistry Photobiomodulation Oral Lichen Planus Topical Steroid Diode Laser |
| title | Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus |
| title_full | Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus |
| title_fullStr | Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus |
| title_full_unstemmed | Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus |
| title_short | Effectiveness of low-level laser therapy and topical steroid therapy in the management of oral lichen planus |
| title_sort | effectiveness of low level laser therapy and topical steroid therapy in the management of oral lichen planus |
| topic | Photobiomodulation Oral Lichen Planus Topical Steroid Diode Laser |
| url | https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3914 |
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